[摘 要]目的 探究聚左旋乳酸联合蜂巢皮秒激光治疗痤疮凹陷性瘢痕的临床效果。方法 选取2019年1月-2020年12月于厦门思明极光美学医疗美容诊所就诊的48例痤疮凹陷性瘢痕患者为研究对象，采用随机数字表法分为对照组与观察组，每组24例。对照组给予蜂巢皮秒激光，观察组先采取聚左旋乳酸局部注射，随后使用蜂巢皮秒激光，比较两组临床疗效、治疗满意度及不良反应发生情况。结果 观察组治疗总有效率为95.83%，高于对照组的87.50%，差异有统计学意义(P<0.05)；观察组满意度高于对照组，差异有统计学意义(P<0.05)；观察组不良反应发生率为12.50%，略高于对照组的8.33%，但差异无统计学意义(P>0.05)。结论 聚左旋乳酸联合蜂巢皮秒激光治疗痤疮凹陷性瘢痕疗效确切，可提高患者满意度，且耐受性好，不会增加不良反应发生几率，值得临床应用。

    [关键词] 聚左旋乳酸微球；蜂巢皮秒；痤疮凹陷性瘢痕

    [中图分类号] R758.73+3 [文献标识码] A [文章编号] 1004-4949(2024)13-0062-04

    Clinical Effect of Poly-L-lactic Acid Combined with PicoSure Laser in the Treatment of Acne Depressed Scars

    YAN Chong-wen

    (Xiamen Siming Jiguang Aesthetics Medical Beauty Clinic， Xiamen 361001， Fujian， China)

    [Abstract]Objective To explore the clinical effect of poly-L-lactic acid combined with PicoSure laser in the treatment of acne depressed scars. Methods A total of 48 patients with acne depressed scars who were treated in Xiamen Siming Jiguang Aesthetic Medical Beauty Clinic from January 2019 to December 2020 were selected as the research objects. They were divided into control group and observation group by random number table method ......