[摘 要]目的 探讨调Q激光联合纳晶微针导入氨甲环酸治疗黄褐斑的临床效果。方法 选取2023年1月-2024年1月崇左市人民医院收治的70例黄褐斑患者作为研究对象，随机分为对照组和观察组，每组35例。对照组采用调Q激光治疗，观察组在此基础上采用纳晶微针导入氨甲环酸治疗，比较两组临床疗效、黄褐斑改善情况、不良反应发生率。结果 观察组治疗总有效率为77.14%，高于对照组的51.43%，差异有统计学意义(P<0.05)；观察组治疗后MASI评分为(6.31±1.05)分，低于对照组的(8.24±2.19)分，差异有统计学意义(P<0.05)；两组不良反应发生率比较，差异无统计学意义(P>0.05)。结论 调Q激光联合纳晶微针导入氨甲环酸治疗黄褐斑的临床效果较好，能改善面部皮损状况，且安全性较好，值得临床应用。

    [关键词] 纳晶微针；氨甲环酸；调Q激光；黄褐斑

    [中图分类号] R758.4+2 [文献标识码] A [文章编号] 1004-4949(2024)14-0038-04

    Application Value of Q-switched Laser Combined with Nanocrystalline Microneedle Introduction of Tranexamic Acid in Patients with Chloasma

    ZHANG Gui-jin

    (Department of Dermatology， the People’s Hospital of Chongzuo， Chongzuo 532200， Guangxi， China)

    [Abstract]Objective To investigate the clinical effect of Q-switched laser combined with nanocrystalline microneedle introduction of tranexamic acid in the treatment of chloasma. Methods A total of 70 patients with chloasma admitted to the People’s Hospital of Chongzuo from January 2023 to January 2024 were randomly divided into control group and observation group， with 35 patients in each group. The control group was treated with Q-switched laser. On this basis ......