[摘 要]目的 探讨尿素乳膏与复方多粘菌素B软膏在面部脂溢性皮炎患者中的应用效果。方法 选取2023年2月-2024年2月我院收治的64例面部脂溢性皮炎患者作为研究对象，按随机数字表法分为对照组和研究组，每组32例。对照组应用尿素乳膏治疗，研究组应用复方多粘菌素B软膏治疗，比较两组临床疗效、皮损评分、皮肤含水量、经皮水分散失、皮肤酸碱度、皮脂分泌量。结果 研究组治疗总有效率(96.88%)高于对照组(90.63%)(P<0.05)；研究组皮损评分低于对照组(P<0.05)；研究组皮肤含水量高于对照组，TEWL值低于对照组(P<0.05)；两组皮肤酸碱度比较，差异无统计学意义(P>0.05)；研究组皮脂分泌量高于对照组(P<0.05)。结论 对于皮肤干燥、脱屑严重的面部脂溢性皮炎患者，使用复方多粘菌素B软膏效果更佳；对于皮肤酸碱度失衡、容易引发炎症或皮脂分泌旺盛的面部脂溢性皮炎患者，使用尿素乳膏效果更佳；对于提升皮肤美学效果，单独或联合使用复方多粘菌素B软膏效果更佳。

    [关键词] 尿素乳膏；复方多粘菌素B软膏；面部脂溢性皮炎；皮肤美容

    [中图分类号] R758.73+2 [文献标识码] A [文章编号] 1004-4949(2024)15-0039-04

    Clinical Effect of Urea Cream and Compound Polymyxin B Ointment in the Treatment of Patients with Facial Seborrheic Dermatitis

    JIA Yu-e， LI Jing， LIU Yu-qi

    (Pharmacy Department of Peking University First Hospital Ningxia Women and Children’s Hospital/Ningxia Hui Autonomous Region Maternal and Child Health Hospital， Yinchuan 750000， Ningxia， China)

    [Abstract]Objective To explore the application effect of urea cream and compound polymyxin B ointment in patients with facial seborrheic dermatitis. Methods A total of 64 patients with facial seborrheic dermatitis admitted to our hospital from February 2023 to February 2024 were selected as the research objects. According to the random number table method ......