[摘 要]目的 探究重组胶原蛋白皮肤修复液在二氧化碳点阵激光术后创面修复中的应用效果及对色素沉着的改善效果。方法 选择2022年6月-2023年6月于我院进行二氧化碳点阵激光术治疗的126例患者，随机分为观察组和对照组，每组63例。对照组采用常规修复，观察组术后采用重组胶原蛋白皮肤修复液修复，比较两组急性炎症反应情况、疼痛情况(VAS)、创面愈合时间、VISIA皮肤图像、不良反应发生率。结果 观察组术后0.5 h、术后1 d的红斑灼热感评分均低于对照组(P<0.05)，观察组的创面愈合时间短于对照组(P<0.05)；观察组术后0.5 h、术后1 d、3 d的VAS评分均低于对照组(P<0.05)；两组术后1个月的VISIA皮肤图像的红斑、棕色斑、纹理评分均低于术前(P<0.05)，且观察组均低于对照组(P<0.05)；观察组不良反应发生率为4.76%，低于对照组的15.87%(P<0.05)。结论 重组胶原蛋白皮肤修复液可有效促进二氧化碳点阵激光术后患者的创面修复，并可减少色素沉着的发生。

    [关键词] 重组胶原蛋白皮肤修复液；二氧化碳点阵激光；创面修复；色素沉着

    [中图分类号] R364.2+3 [文献标识码] A [文章编号] 1004-4949(2024)15-0043-04

    Application Effect of Recombinant Collagen Skin Repair Solution in Wound Repair After Carbon Dioxide Fractional Laser Surgery and its Improvement Effect on Pigmentation

    LIU Su-xia

    (Dermatology Department of Ruyang County People’s Hospital， Luoyang 471200， Henan， China)

    [Abstract]Objective To explore the application effect of recombinant collagen skin repair solution in wound repair after carbon dioxide fractional laser surgery and its improvement effect on pigmentation. Methods A total of 126 patients who underwent carbon dioxide fractional laser surgery in our hospital from June 2022 to June 2023 were randomly divided into observation group and control group ......