[摘 要]目的 分析在唇腭裂修复术中应用右美托咪定的效果。方法 选取2023年5月-2024年4月本院收治的62例唇腭裂患儿，随机分为A组和B组，每组31例。患儿均在气管插管全麻下行唇腭裂修复术，术前10 min时，A组以静脉泵注的方式给予小儿糖盐水(0.2 mg/kg)，B组以相同方式且等容积给予右美托咪定，比较两组血流动力学指标、疼痛与镇静评分、拔管后不良反应发生情况。结果 B组T2～T4时MAP低于A组，T2～T5时HR低于对照组(P<0.05)；B组T4、T5时疼痛评分低于A组，镇静评分高于A组(P<0.05)；B组拔管后不良反应发生率为3.23%，低于A组的25.81%(P<0.05)。结论 右美托咪定在唇腭裂修复术中应用效果确切，可维持血流动力学稳定，减轻疼痛，且镇静效果良好，拔管后不良反应发生率较低，应用安全性较高。

    [关键词] 唇腭裂修复术；右美托咪定；血流动力学；镇静

    [中图分类号] R782.05+4 [文献标识码] A [文章编号] 1004-4949(2024)15-0131-04

    Application Effect of Dexmedetomidine in Cleft Lip and Palate Repair Surgery

    JIN Chun-hua

    (Department of Anesthesiology， Suzhou Benq Hospital， Suzhou 215009， Jiangsu， China)

    [Abstract]Objective To analyze the anesthetic effect of dexmedetomidine in cleft lip and palate repair. Methods A total of 62 children with cleft lip and palate admitted to our hospital from May 2023 to April 2024 were randomly divided into group A and group B， with 31 children in each group. All patients underwent cleft lip and palate repair under general anesthesia with tracheal intubation. At 10 min before operation， group A was given intravenous infusion of pediatric sugar saline (0.2 mg/kg) ......