[摘 要]目的 探讨在中度痤疮患者中采用强脉冲光联合夫西地酸乳膏治疗的效果。方法 选取2022年9月-2023年9月我院收治的72例中度痤疮患者为研究对象，采用随机数字表法分为对照组与观察组，各36例。对照组实施强脉冲光治疗，观察组在对照组基础上实施夫西地酸乳膏治疗，比较两组临床疗效、皮肤症状积分、炎性因子水平、生活质量。结果 观察组总有效率为97.22%，高于对照组的77.78%(P<0.05)；观察组治疗后粉刺、炎性丘疹、脓疱评分低于对照组(P<0.05)；观察组治疗后IL-1、IL-6、TNF-α水平低于对照组(P<0.05)；观察组治疗后生活质量评分为(93.27±4.64)分，高于对照组的(88.75±5.32)分(P<0.05)。结论 在中度痤疮患者中采用强脉冲光联合夫西地酸乳膏治疗的效果确切，能改善患者皮肤症状，降低炎症因子水平，提高患者生活质量，值得临床应用。

    [关键词]强脉冲光；夫西地酸乳膏；中度痤疮

    [中图分类号] R758.73+3 [文献标识码] A [文章编号] 1004-4949(2024)17-0013-04

    Clinical Effect of Intensive Pulsed Light Combined with Fusidic Acid Cream in the Treatment of Moderate Acne

    HU Kai， LU Hong-yu， WU Wei， HUAN Jia-jun

    (Dermatology Department of Eastern Theater Command Air Force Hospital， Nanjing 210000， Jiangsu， China)

    [Abstract]Objective To investigate the effect of intensive pulsed light combined with fusidic acid cream in patients with moderate acne. Methods A total of 72 patients with moderate acne admitted to our hospital from September 2022 to September 2023 were selected as the research objects. They were divided into control group and observation group by random number table method ......