[摘 要]目的 观察在黄褐斑治疗中应用自拟疏肝健脾补肾活血汤联合黄褐斑贴敷料的效果及安全性。方法 选取2023年3月-2024年3月我院收治的70例黄褐斑患者为研究对象，以随机数字表法分为对照组和观察组，各35例。对照组行常规西医治疗，观察组行自拟疏肝健脾补肾活血汤联合黄褐斑贴敷料治疗，比较两组临床疗效、不良反应发生情况、中医证候积分及皮损恢复情况。结果 观察组治疗总有效率为97.14%，高于对照组的82.86%(P<0.05)；观察组不良反应发生率为5.71%，低于对照组的22.86%(P<0.05)；观察组治疗后急躁易怒、胸胁胀痛、颜面黄斑积分均低于对照组(P<0.05)；观察组治疗后MASI评分低于对照组(P<0.05)。结论 自拟疏肝健脾补肾活血汤联合黄褐斑贴敷料治疗黄褐斑的效果理想，不良反应少，安全性高，可有效改善患者的黄褐斑症状，促进皮损恢复。

    [关键词] 黄褐斑；自拟疏肝健脾补肾活血汤；黄褐斑贴敷料

    [中图分类号] R758.4+2 [文献标识码] A [文章编号] 1004-4949(2024)17-0032-04

    Effect of Self-made Shugan Jianpi Bushen Huoxue Decoction Combined with Chloasma Dressing in the Treatment of Chloasma

    MIAO Li1， GU Dan2

    (1.Preparation Center of Yinchuan City Hospital of Traditional Chinese Medicine， Yinchuan 750001， Ningxia， China； 2.Department of Pharmaceutical， Xi’an Weiyang Baoshihua Xinglongyuan Hospital， Xi’an 710016， Shaanxi， China)

    [Abstract]Objective To observe the effect and safety of self-made Shugan Jianpi Bushen Huoxue decoction combined with chloasma dressing in the treatment of chloasma. Methods A total of 70 patients with chloasma admitted to our hospital from March 2023 to March 2024 were selected as the research objects and divided into control group and observation group by random number table method ......