[摘 要]目的 探讨对皮肤光老化患者应用强脉冲光联合点阵CO2激光治疗的效果。方法 选择2022年5月-2024年2月徐州华美美容医院美容皮肤科收治的78例皮肤光老化患者为研究对象，根据随机数字表法分为对照组和观察组，每组39例。对照组予以强脉冲光治疗，观察组予以强脉冲光联合点阵CO2激光治疗，比较两组临床疗效、皮肤状态改善程度及不良反应发生情况。结果 观察组治疗总有效率为97.44%，高于对照组的82.05%，差异有统计学意义(P<0.05)；观察组治疗后GAIS评分高于对照组，GSP评分低于对照组，差异有统计学意义(P<0.05)；两组不良反应发生率比较，差异无统计学意义(P>0.05)。结论 强脉冲光联合点阵CO2激光治疗皮肤光老化的效果良好，能有效改善患者的皮肤状态，且不会增加不良反应发生几率，值得临床应用。

    [关键词] 强脉冲光；点阵CO2激光；皮肤光老化

    [中图分类号] R62 [文献标识码] A [文章编号] 1004-4949(2024)18-0046-04

    Effect of Intensive Pulsed Light Combined with CO2 Fractional Laser in the Treatment of Skin Photoaging

    WANG Yuqing1， ZHEN Qi2

    (1.Cosmetic Dermatology Department of Xuzhou Huamei Beauty Hospital， Xuzhou 221001， Jiangsu， China； 2.Cosmetic Dermatology Department of Chongqing Opu Medical Beauty Clinic， Chongqing 400711， China)

    [Abstract]Objective To investigate the effect of intensive pulsed light combined with CO2 fractional laser in the treatment of skin photoaging. Methods A total of 78 patients with skin photoaging admitted to the Department of Cosmetic Dermatology， Xuzhou Huamei Beauty Hospital from May 2022 to February 2024 were selected as the research objects. According to the random number table method ......