[摘 要]目的 比较5.0 mg/ml浓度和2.5 mg/ml浓度的透明质酸中胚层疗法在面部年轻化中的效果差异。方法 选取2022年4月-2023年12月于我院接受面部年轻化美容的89例患者为研究对象，随机分为观察组(45例)与对照组(44例)。对照组以5.0 mg/ml浓度的透明质酸进行中胚层疗法干预，而观察组以2.5 mg/ml浓度的透明质酸进行中胚层疗法干预，比较两组皮肤状态和不良反应。结果 观察组干预后皱纹、毛孔、斑点评分优于对照组(P<0.05)；观察组不良反应发生率为4.44%，低于对照组的22.73%(P<0.05)。结论 将2.5 mg/ml浓度的透明质酸中胚疗法治疗面部年轻化可更好的改善皱纹、毛孔、斑点等情况，而且能减少出现不良反应的风险，值得临床应用。

    [关键词] 透明质酸；中胚疗法；面部年轻化

    [中图分类号] R622 [文献标识码] A [文章编号] 1004-4949(2024)18-0082-03

    Clinical Effect of Different Concentrations of Hyaluronic Acid Mesotherapy in Facial Rejuvenation

    YANG Shu

    (Xinjiekou Medical Cosmetology Clinic of Nanjing Jinying International Health Industry Group， Nanjing 210000， Jiangsu， China)

    [Abstract]Objective To compare the effects of 5.0 mg/ml and 2.5 mg/ml hyaluronic acid mesotherapy on facial rejuvenation. Methods A total of 89 patients who received facial rejuvenation in our hospital from April 2022 to December 2023 were randomly divided into observation group (45 patients) and control group (44 patients). The control group was treated with 5.0 mg/ml hyaluronic acid for mesotherapy intervention ......