[摘 要]目的 探讨带蒂皮瓣联合封闭负压引流技术修复难治性创面的临床疗效。方法 选择本院2020年1月-2022年12月收治的45例难治性创面患者为研究对象，随机分为对照组(22例)与试验组(23例)。对照组应用带蒂皮瓣修复，试验组应用带蒂皮瓣联合封闭负压技术修复，比较两组临床相关指标及术后并发症发生情况。结果 试验组术前准备时间、换药次数、创面愈合时间、抗生素使用时间及住院总费用均优于对照组(P<0.05)；两组术中出血量比较，差异无统计学意义(P>0.05)；试验组并发症发生率为21.74%，低于对照组的31.82%，但差异无统计学意义(P>0.05)。结论 带蒂皮瓣联合术后封闭负压引流技术治疗难治性创面安全有效，可缩短创面愈合时间，减少抗生素使用时间，改善创面感染，且不会增加并发症发生风险，值得临床应用。

    [关键词] 带蒂皮瓣；封闭负压引流；难治性创面

    [中图分类号] R641 [文献标识码] A [文章编号] 1004-4949(2024)20-0016-04

    Clinical Effect of Pedicled Flap Combined with Vacuum Sealing Drainage in Repairing Refractory Wounds

    ZHANG Qiangqiang， WEN Zhiguo， TANG Mengyan

    (Xinxiang Medical College Luoyang Central Hospital， Xinxiang 453003， Henan， China)

    [Abstract]Objective To investigate the clinical efficacy of pedicled flap combined with vacuum sealing drainage in the repair of refractory wounds. Methods A total of 45 patients with refractory wounds admitted to our hospital from January 2020 to December 2022 were randomly divided into control group (22 patients) and experimental group (23 patients). The control group was repaired with pedicle flap ......