[摘 要]目的 观察桃红四物汤加减联合超皮秒激光治疗气滞血瘀型黄褐斑的临床效果。方法 选取2022年1月-2023年12月我院接诊的52例黄褐斑患者为研究对象，采用随机数字表法分为对照组和观察组，各组26例。对照组采用超皮秒激光治疗，观察组在对照组基础上联合应用桃红四物汤加减治疗，比较两组治疗临床疗效、黄褐斑面积、黄褐斑颜色评分、色斑残留情况评分(PGA)、皮肤病生活质量指数(DLQI)、中医症候积分及临床不良反应发生率。结果 观察组治疗总有效率为96.15%，高于对照组的80.77%(P<0.05)；观察组治疗后黄褐斑面积、黄褐斑颜色评分、PGA评分、DLQI评分、中医症候积分均低于对照组(P<0.05)；观察组不良反应发生率与对照组比较，差异无统计学意义(P>0.05)。结论 桃红四物汤加减联合超皮秒激光治疗气滞血瘀型黄褐斑的临床效果确切，可降低中医证候积分、PGA及黄褐斑颜色评分，缩小黄褐斑面积，改善患者生活质量，且不会增加不良反应。

    [关键词] 桃红四物汤；超皮秒激光；气滞血瘀型；黄褐斑

    [中图分类号] R758.4+2 [文献标识码] A [文章编号] 1004-4949(2024)20-0056-04

    Clinical Effect of Modified Taohong Siwu Decoction Combined with Picosecond Laser in the Treatment of Chloasma of Qi Stagnation and Blood Stasis Type

    TAO Linchang， LAN Junzhu， CHEN Huiru， CHEN Yujian， LIAO Yeqing

    (Department of Cosmetology and Traditional Chinese Medicine， Guangxi Zhuang Autonomous Region Dermatology Hospital， Nanning 530007， Guangxi， China)

    [Abstract]Objective To observe the clinical effect of modified Taohong Siwu decoction combined with picosecond laser on CHloasma of qi stagnation and blood stasis type. Methods A total of 52 patients with chloasma who were admitted to our hospital from January 2022 to December 2023 were selected as the research objects. They were divided into control group and observation group by random number table method ......