[摘 要]目的 探究在黄褐斑患者中应用强脉冲光联合氨甲环酸治疗的效果及对患者皮损面积、皮损颜色的影响。方法 选取厦门思明王炳南九九医疗美容诊所2022年7月-2023年7月收治的70例黄褐斑患者为研究对象，以随机数字表法分为对照组(n=35)和观察组(n=35)。对照组采用氨甲环酸治疗，观察组采用强脉冲光联合氨甲环酸治疗，比较两组临床疗效、皮损面积、皮损颜色、生活质量及治疗满意度。结果 观察组治疗总有效率为97.14%，高于对照组的82.86%(P<0.05)；观察组皮损面积评分、皮损颜色评分均低于对照组(P<0.05)；观察组SF-36各维度评分均高于对照组(P<0.05)；观察组治疗满意度为97.14%，高于对照组的80.00%(P<0.05)。结论 强脉冲光联合氨甲环酸治疗黄褐斑的效果良好，可缩小黄褐斑皮损面积，淡化皮损颜色，有利于改善患者的生活质量，提高治疗满意度。

    [关键词] 黄褐斑；强脉冲光；氨甲环酸；皮损面积；皮损颜色

    [中图分类号] R758.4+2 [文献标识码] A [文章编号] 1004-4949(2024)21-0071-04

    Effect of Intensive Pulsed Light Combined with Oral Tranexamic Acid on Skin Lesion Area and Skin Lesion Color in Patients with Chloasma

    WANG Jun

    (Xiamen Siming Wang Bingnan 99 Medical Beauty Clinic， Xiamen 361000， Fujian， China)

    [Abstract]Objective To explore the effect of intensive pulsed light combined with tranexamic acid in patients with chloasma and its effect on skin lesion area and skin lesion color. Methods A total of 70 patients with chloasma admitted to Xiamen Siming Wang Bingnan 99 Medical Beauty Clinic from July 2022 to July 2023 were selected as the research objects and divided into control group(n=35) and observation group (n=35) by random number table method. The control group was treated with tranexamic acid ......