[摘 要]目的 探讨在痤疮患者治疗中应用丹参酮联合盐酸四环素的效果及对血清性激素水平、皮脂分泌率的影响。方法 选取宁强县天津医院2023年1月-12月收治的60例痤疮患者为研究对象，随机分为对照组和观察组，每组30例。对照组给予盐酸四环素治疗，观察组给予丹参酮联合盐酸四环素治疗，比较两组皮脂分泌率(SER)、临床疗效、血清素激素水平及心理状态。结果 观察组治疗后SER低于对照组(P<0.05)；观察组治疗总有效率为96.67%，高于对照组的73.33%(P<0.05)；观察组治疗后LH、FSH、E2水平均高于对照组，T水平低于对照组(P<0.05)；观察组治疗后SDS、SAS评分均低于对照组(P<0.05)。结论 在痤疮患者治疗中应用丹参酮联合盐酸四环素的效果良好，可改善患者的血清性激素水平，降低皮脂分泌率，有利于减轻其负面情绪，促进恢复。

    [关键词] 痤疮；丹参酮；盐酸四环素；血清性激素水平；皮脂分泌率

    [中图分类号] R758.73+3 [文献标识码] A [文章编号] 1004-4949(2024)22-0029-04

    Effect of Tanshinone Combined with Tetracycline Hydrochloride on Serum Sex Hormone Levels and Sebum Secretion Rate in Patients with Acne

    LIAO Shaojun

    (Medical Laboratory Department of Ningqiang County Tianjin Hospital， Hanzhong 724400， Shaanxi， China)

    [Abstract]Objective To investigate the effect of tanshinone combined with tetracycline hydrochloride in the treatment of acne patients and its effect on serum sex hormone levels and sebum secretion rate. Methods Sixty patients with acne admitted to Ningqiang County Tianjin Hospital from January to December 2023 were randomly divided into control group and observation group ......