[摘 要]目的 分析对黄褐斑患者应用强脉冲光联合氨甲环酸治疗的有效率及安全性。方法 选取2022年12月-2024年3月我院收治的137例黄褐斑患者为研究对象，随机分为对照组(n=68)和观察组(n=69)。对照组采用强脉冲光治疗，观察组采用强脉冲光联合氨甲环酸治疗，比较两组治疗效果、临床相关指标、不良反应发生情况及复发情况。结果 观察组治疗总有效率(89.86%)高于对照组(73.53%)，差异有统计学意义(P<0.05)；观察组MASI评分、经表皮水分流失量低于对照组，皮肤角质层含水量高于对照组，差异有统计学意义(P<0.05)；两组不良反应发生率比较，差异无统计学意义(P>0.05)；观察组复发率(1.45%)低于对照组(10.29%)，差异有统计学意义(P<0.05)。结论 强脉冲光联合氨甲环酸治疗黄褐斑的有效性及安全性均良好，可改善患者的黄褐斑症状及皮肤状态，且不会增加不良反应发生风险，复发率较低。

    [关键词] 强脉冲光；氨甲环酸；黄褐斑

    [中图分类号] R758.4+2 [文献标识码] A [文章编号] 1004-4949(2024)22-0067-04

    Efficacy and Safety of Intensive Pulsed Light Combined with Tranexamic Acid in the Treatment of Chloasma

    LU Hui

    (Dermatology Department of Jiangsu Changzhou Mylike Medical Beauty Hospital， Changzhou 213000， Jiangsu， China)

    [Abstract]Objective To analyze the efficacy and safety of intensive pulsed light combined with tranexamic acid in the treatment of chloasma. Methods A total of 137 patients with chloasma admitted to our hospital from December 2022 to March 2024 were randomly divided into control group (n=68) and observation group (n=69). The control group was treated with intensive pulsed light ......