[摘 要]目的 探讨VSD负压吸引术联合游离植皮修复治疗Ⅲ、Ⅳ度烧伤对患者感染发生情况的影响。方法 选取2022年8月-2024年8月我院收治的60例Ⅲ、Ⅳ度烧伤患者为研究对象，采用随机数字表法分为对照组与观察组，各30例。对照组采用游离植皮修复治疗，观察组在对照组基础上联合VSD负压吸引术，比较两组临床疗效、炎症因子水平、感染发生情况及瘢痕增生严重程度。结果 观察组治疗总有效率为96.67%，高于对照组的80.00%，差异有统计学意义(P<0.05)；观察组术后7 d IL-6、IL-8和CRP水平低于对照组，差异有统计学意义(P<0.05)；观察组感染发生率为3.33%，低于对照组的16.67%，差异有统计学意义(P<0.05)；观察组瘢痕增生严重程度优于对照组，差异有统计学意义(P<0.05)。结论 采用VSD负压吸引术联合游离植皮修复治疗Ⅲ、Ⅳ度烧伤能够减少患者感染风险，有效减轻瘢痕形成的严重程度，同时降低炎症因子水平，提高治疗效果，具有较好的临床应用价值。

    [关键词] VSD负压吸引术；游离植皮修复；Ⅲ、Ⅳ度烧伤

    [中图分类号] R783.3 [文献标识码] A [文章编号] 1004-4949(2024)22-0087-04

    Effect of VSD Vacuum Aspiration Combined with Free Skin Graft Repair on the Incidence of Infection in Patients with Ⅲ and Ⅳ Degree Burns

    YAN Jiong

    (Burn Trauma Diagnosis and Treatment Center， Affiliated Hospital of Jiangnan University， Wuxi 214000， Jiangsu， China)

    [Abstract]Objective To investigate the effect of VSD vacuum aspiration combined with free skin graft repair on the incidence of infection in patients with Ⅲ and Ⅳ degree burns. Methods A total of 60 patients with Ⅲ and Ⅳ degree burns admitted to our hospital from August 2022 to August 2024 were selected as the research objects. They were divided into control group and observation group by random number table method ......