[摘 要]目的 分析慢性荨麻疹治疗中应用盐酸西替利嗪联合复方甘草酸苷的效果及对患者炎性因子水平的影响。方法 选取我院2022年1月-2023年12月收治的80例慢性荨麻疹患者为研究对象，采用随机数字表法分为对照组与观察组，每组40例。对照组予以盐酸西替利嗪治疗，观察组予以盐酸西替利嗪联合复方甘草酸苷治疗，比较两组临床症状消失时间、炎性因子水平、治疗效果、不良反应发生率及复发率。结果 观察组各项临床症状消失时间短于对照组(P<0.05)；观察组治疗后IL-4、IL-8、IL-17、IL-23水平低于对照组(P<0.05)；观察组治疗总有效率为97.50%，高于对照组的75.00%(P<0.05)；观察组不良反应发生率(2.50%)低于对照组(22.50%)，复发率低于对照组(P<0.05)。结论 应用盐酸西替利嗪联合复方甘草酸苷治疗慢性荨麻疹效果较为确切，可以有效降低不良反应发生几率及疾病复发率，改善机体炎性因子水平，加速临床症状消失，具有较高的临床应用价值。

    [关键词] 慢性荨麻疹；盐酸西替利嗪；复方甘草酸苷；炎性因子

    [中图分类号] R758.24 [文献标识码] A [文章编号] 1004-4949(2024)23-0069-04

    Effect of Cetirizine Hydrochloride Combined with Compound Glycyrrhizin in the Treatment of Chronic Urticaria and its Effect on the Level of Inflammatory Factors

    YUAN Hongyan

    (Pharmacy Department of Beihua University Affiliated Hospital， Jilin 132000， Jilin， China)

    [Abstract]Objective To analyze the effect of cetirizine hydrochloride combined with compound glycyrrhizin in the treatment of chronic urticaria and its effect on the level of inflammatory factors. Methods A total of 80 patients with chronic urticaria admitted to our hospital from January 2022 to December 2023 were selected as the research objects. They were divided into control group and observation group by random number table method ......