肝纤维化中T淋巴细胞对肝星状细胞活化的影响
Effect of T lymphocyte on hepatic stellate cell activation in liver fibrosisGONG Xiaoqian1， WEI Yehuang1， WANG Rongrong1， LIU Xudong2
1.GraduateSchool ofGuangxi UniversityofChineseMedicine，Nanning53ooo1，China
2. Department ofLiver Disease，Ruikang Hospital Affliated to Guangxi Universityof Chinese Medicine，
Nanning530011，China
Correspondingauthor： LIU Xudong， Email： lxdlhx@163.com
【Abstract】Liver fibrosis is a repair reaction of the whole body after liver injury caused by many causes (such as viral hepatitis and metabolic dysfunction-associated steatotic liver disease). It is mainly manifested as excessive proliferation and deposition of extracellular matrix in liver tissue，which leads to abnormal changes in liver tissue structure，cirrhosis and liver failure，and affects the normal physiological function of liver.Activated hepatic stellate cels (HSC) are generally considered to be the main celltype that forms liver fibrosis.During liver fibrosis，immune cells play an important role in regulating the activation of HSC，such as interleukin17 (IL-17)， IL-10 and transforming growth factor β ......
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