子宫内膜异位症病灶神经纤维分布的研究(3)
EMs疼痛的發生有很多原因，本研究只是从神经纤维的分布进行了分析，说明不同病灶组织中神经纤维数目与疼痛有一定的相关性，神经纤维数目的增加在内异症疼痛的发生中起到一定的作用，其与病灶中异位内膜腺体或间质的生长、神经递质或致痛因子的分泌等因素相互关联，共同参与疼痛的发生机制，这也是我们将来需要进一步研究的问题。
参考文献：(References)
[1] Karen JB, Andrea JR, Raymond EP. The pains of endometriosis[J].Science,2005,308(5728):1587-1589.
[2] Sepulcri Rde P, Amaral VF. Depressive symptoms, anxiety, and quality of life in women with pelvic endometriosis. Eur J Obstet Gynecol Reprod Bio[J]. 2009 Jan;142(1):53-6.
[3] Porpora MG, Pallante D, Ferro A Pain and ovarian endometrioma recurrence after aparoscopic treatment of endometriosis: a long-term prospective study Fertil Steril[J].2008 Dec 3.
[4] Tran LV, Tokushige N, Berbic M Macrophages and nerve fibers in peritoneal endometriosis Hum Reprod[J]. 2009 Jan 9.
[5] Natsuko T, Robert M, Peter R et al. Nerve fibers in peritoneal endometriosis. Human Reprod [J] 2006,21(11):3001-3007.
[6] Anaf. V, Simon. P, EL Nakadi. I et al Hyperalgesia, nerve infiltration and nerve growth factor expression in deep adenomyotic nodules, peritoneal and ovarian endometriosis. Human Reprod [J] 2002,17(7), 1895-1900., http://www.100md.com(袁惠芝 柳晓春 王夷黎 张汝坚 陈永连)
参考文献：(References)
[1] Karen JB, Andrea JR, Raymond EP. The pains of endometriosis[J].Science,2005,308(5728):1587-1589.
[2] Sepulcri Rde P, Amaral VF. Depressive symptoms, anxiety, and quality of life in women with pelvic endometriosis. Eur J Obstet Gynecol Reprod Bio[J]. 2009 Jan;142(1):53-6.
[3] Porpora MG, Pallante D, Ferro A Pain and ovarian endometrioma recurrence after aparoscopic treatment of endometriosis: a long-term prospective study Fertil Steril[J].2008 Dec 3.
[4] Tran LV, Tokushige N, Berbic M Macrophages and nerve fibers in peritoneal endometriosis Hum Reprod[J]. 2009 Jan 9.
[5] Natsuko T, Robert M, Peter R et al. Nerve fibers in peritoneal endometriosis. Human Reprod [J] 2006,21(11):3001-3007.
[6] Anaf. V, Simon. P, EL Nakadi. I et al Hyperalgesia, nerve infiltration and nerve growth factor expression in deep adenomyotic nodules, peritoneal and ovarian endometriosis. Human Reprod [J] 2002,17(7), 1895-1900., http://www.100md.com(袁惠芝 柳晓春 王夷黎 张汝坚 陈永连)