MSCT在评价慢性阻塞性肺疾病合并支气管扩张患者肺功能中的作用(1)
【摘 要】目的：探讨MSCT(multi-slice spiral CT)在评价慢性阻塞性肺疾病(chronic obstruction pulmonary disease ，COPD)合并支气管扩张患者肺功能中的作用。方法：随机选取我院自2015年1月-2016年12月呼吸内科收治的COPD合并支气管扩张患者30例作为观察组，选取同时期同期接受体检的健康志愿者30例为对照组。为入选者均进行MSCT和肺功能检查。观察受检者的MSCT指标、肺功能指标及观察组患者的支气管扩张情况。结果：观察组患者的MSCT各肺容积指标Vin、Vex、(Vin-Vex)、Vin/Vex、(Vin-Vex)/Vin均明显高于对照组(P<0.05)；观察组患者MSCT肺容积指标与肺功能指标(FEV1%pred、FEV1/FVC)之间有良好的相关性；观察组患者支气管扩张柱状型10例，囊状型12例，混合型8例。结论：MSCT扫描不仅能客观了解COPD合并支气管扩张患者支气管扩张情况，也能很好地评估COPD合并支气管扩张患者的肺功能情况，并为临床诊断、治疗、预后评估提供客观依据，是首选的检查方法。
, 百拇医药
【关键词】MSCT；慢性阻塞性肺疾病；支气管扩张；肺功能
abstract：Objective： Discuss the action of MSCT in the evaluation of pulmonary function in patients with chronic obstruction pulmonary disease complicated with bronchiectasis. Methods 30 patients of COPD combined bronchiectasis selected from January 2015 to December 2016 in our hospital respiratory medicine were considered as the observation group， the other to choose medicine examination at the same period of 30 cases of healthy volunteer as control group. All of them were examined for MSCT and pulmonary function tests. The MSCT indicator， lung function and bronchiectasis situation of observation group were observed. Results The lung volume of MSCT the Vin， Vex，lung volume index(Vin-Vex)，in/Vex，(Vin-Vex)/Vin in the observation group were significantly higher than in the control group(P<0.05)；Observation group of MSCT in patients with lung volume index and pulmonary function index (FEV1%pred， FEV1/FVC) has a good correlation between ；10 cases had cylindrical bronchiectasis，12 cases had saccate type，8 cases had mixed type.Conclusion MSCT scan can not only objectively understand COPD and bronchiectasis patients，also can well evaluate the pulmonary function of COPD patients with bronchiectasis and provide objective basis for clinical diagnosis，treatment and evaluation of prognosis，is the preferred examination method.
, 百拇医药
Key words： Multi-slice spiral CT；Chronic obstructive pulmonary disease；bronchiectasis；pulmonary function
【中圖分类号】R969.3 【文献标识码】A 【文章编号】1005-0019(2018)02-00-01
慢性阻塞性肺疾病(chronic obstructive pulmonary disease，COPD)是临床上常见的呼吸系统慢性病，是一种以气流受限不完全可逆为特征、呈进行性发展的疾病。支气管扩张症是一种阻塞性通气障碍性病变，多是中、小支气管的管腔出现不可逆扩大[1]。2014年全球慢性阻塞性肺疾病指南(Global Initiative for chronic obstructive pulmonary disease， GOLD)首次将支气管扩张症列入COPD的合并症，并指出其与COPD急性加重时间延长、死亡率增加有关。Agusti[2]等进行的一项跨国纵向评价识别预测替代终点(Eclipse)研究发现，所有GOLD分期的COPD患者合并支气管扩张的患病率为4%，且该患病率随着GOLD 分期等级的增加而增高。林庆育[3]等的研究发现COPD合并支气管扩张组患者主要表现为阻塞性通气功能障碍，患者肺功能相关指标包括FEV1% pred、FEV1 /FVC降低更为明显，及气流受限更为严重。目前临床上多通过肺功能检查的相关性指标及临床表现等判断气道阻塞的程度，评价两肺的受损之和。随着多层螺旋CT(MSCT)的面世，利用高端影像设备进行肺功能检查与分析已逐渐成为国际上研究的热点[4]。我院采用64排MSCT进行定量分析COPD合并支气管扩张患者的肺功能情况，并通过图像判断支气管扩张情况。现分析如下：, http://www.100md.com(蔡亚男)
, 百拇医药
【关键词】MSCT；慢性阻塞性肺疾病；支气管扩张；肺功能
abstract：Objective： Discuss the action of MSCT in the evaluation of pulmonary function in patients with chronic obstruction pulmonary disease complicated with bronchiectasis. Methods 30 patients of COPD combined bronchiectasis selected from January 2015 to December 2016 in our hospital respiratory medicine were considered as the observation group， the other to choose medicine examination at the same period of 30 cases of healthy volunteer as control group. All of them were examined for MSCT and pulmonary function tests. The MSCT indicator， lung function and bronchiectasis situation of observation group were observed. Results The lung volume of MSCT the Vin， Vex，lung volume index(Vin-Vex)，in/Vex，(Vin-Vex)/Vin in the observation group were significantly higher than in the control group(P<0.05)；Observation group of MSCT in patients with lung volume index and pulmonary function index (FEV1%pred， FEV1/FVC) has a good correlation between ；10 cases had cylindrical bronchiectasis，12 cases had saccate type，8 cases had mixed type.Conclusion MSCT scan can not only objectively understand COPD and bronchiectasis patients，also can well evaluate the pulmonary function of COPD patients with bronchiectasis and provide objective basis for clinical diagnosis，treatment and evaluation of prognosis，is the preferred examination method.
, 百拇医药
Key words： Multi-slice spiral CT；Chronic obstructive pulmonary disease；bronchiectasis；pulmonary function
【中圖分类号】R969.3 【文献标识码】A 【文章编号】1005-0019(2018)02-00-01
慢性阻塞性肺疾病(chronic obstructive pulmonary disease，COPD)是临床上常见的呼吸系统慢性病，是一种以气流受限不完全可逆为特征、呈进行性发展的疾病。支气管扩张症是一种阻塞性通气障碍性病变，多是中、小支气管的管腔出现不可逆扩大[1]。2014年全球慢性阻塞性肺疾病指南(Global Initiative for chronic obstructive pulmonary disease， GOLD)首次将支气管扩张症列入COPD的合并症，并指出其与COPD急性加重时间延长、死亡率增加有关。Agusti[2]等进行的一项跨国纵向评价识别预测替代终点(Eclipse)研究发现，所有GOLD分期的COPD患者合并支气管扩张的患病率为4%，且该患病率随着GOLD 分期等级的增加而增高。林庆育[3]等的研究发现COPD合并支气管扩张组患者主要表现为阻塞性通气功能障碍，患者肺功能相关指标包括FEV1% pred、FEV1 /FVC降低更为明显，及气流受限更为严重。目前临床上多通过肺功能检查的相关性指标及临床表现等判断气道阻塞的程度，评价两肺的受损之和。随着多层螺旋CT(MSCT)的面世，利用高端影像设备进行肺功能检查与分析已逐渐成为国际上研究的热点[4]。我院采用64排MSCT进行定量分析COPD合并支气管扩张患者的肺功能情况，并通过图像判断支气管扩张情况。现分析如下：, http://www.100md.com(蔡亚男)
参见：首页 > 医疗版 > 疾病专题 > 呼吸内科 > 气管、支气管疾病 > 支气管扩张