【摘 要】目的：探讨茴拉西坦联合暴露疗法对创伤后应激障碍病人的疗效和生理指标的影响。方法：选取30名创伤后应激障碍患者，将其随机分为实验组(n=15)和对照组(n=15)，实验组应用暴露治疗结合茴拉西坦方案，对照组应用暴露治疗结合安慰剂方案，治疗12周。分别在治疗前和治疗结束时用PTSD检查表平时版(ThePTSDCheeklist-CivilianVersion，PCL-C)及血压和心律的改变评定治疗效果。结果：治疗结束后两组患者的PCL-C分数均较各自治疗前降低(P<0.05)；实验组的PCL-C分数低于对照组(P<0.05)，其中创伤经历反复重现、回避两个因子分低于对照组(P<0.05)，而在警觉性增高方面两组无差异。两组患者血压及心率在治疗后均有所下降，但实验组和对照组相比并无明显差异。结论：茴拉西坦在一定程度上可以增加暴露治疗的效应量，改善创伤后应激障碍的症状。

    【关键词】创伤后应激障碍；茴拉西坦；暴露疗法；疗效；生理指标

    Abstract：Objective To investigate the effects of aniracetam combined with exposure therapy on the efficacy and physiological indexes of patients with post-traumatic stress disorder.Methods： Thirty patients with post-traumatic stress disorder were randomly divided into experimental group (n=15) and control group (n=15).The experimental group was treated with exposure treatment combined with aniracetam and the control group was treated with exposure treatment.Placebo regimen for 12 weeks of treatment.The therapeutic effects were assessed by PTSD Cheeklist-Civilian Version (PCL-C) and changes in blood pressure ......