【摘 要】目的：探究艾司西酞普兰联合喹硫平在抑郁症治疗中的临床效果。方法：选取本院精神科2016年9月～2019年3月间收治的抑郁症患者116例作为主要研究对象，分为对照组和试验组。对照组患者给予单纯艾司西酞普兰治疗方案，试验组患者给予艾斯西酞普兰联合喹硫平治疗方案。结果：;治疗后，两组患者的HAMD评分均出现显著下降，但对照组患者的HAMD评分明显高于试验组患者。治疗后，两组患者的BRPS评分均出现显著下降，但对照组患者的BRPS评分明显高于试验组患者。两组患者TESS评分无明显差异。结论：艾司西酞普兰与喹硫平在抑郁症患者治疗中联合应用不仅能提高抑郁症治疗效果，同时也能改善患者的精神病症状，且安全性较好，值得在临床治疗中推广应用。

    【关键词】抑郁症;喹硫平;艾司西酞普兰;治疗效果

    Abstract：Objective To investigate the clinical effect of escitalopram combined with quetiapine in the treatment of depression. Methods： A total of 116 patients with depression who were admitted to the psychiatric department from September 2016 to March 2019 were selected as the main subjects and divided into the control group and the experimental group. Patients in the control group were given a simple escitalopram treatment regimen ......