【摘 要】目的：探讨综合干预对处于焦虑、抑郁状态的老年性痴呆(AD)照料者生活质量和焦虑抑郁病情的缓解作用。方法：对56名AD患者的照料者进行为期6个月的综合干预，干预前后对所有照料者分别进行焦虑自评量表(SAS)、抑郁自评量表(SDS)、照料者负担量表(ZBI)、世界卫生组织生活质量测定简表(WHOQOL-BREF)评估，检验综合干预的效果。结果：6个月的干预后，处于焦虑、抑郁状态的AD照料者SAS、SDS、ZBI分值较干预前明显下降，WHOQOL-BREF中健康状况主观感觉、生理领域、心理领域的分值较干预前显著提高(P<0.05)。结论：综合干预对缓解AD照料者焦虑抑郁病情、提高生活质量、减轻照料负担具有较好的作用。

    【关键词】老年痴呆照料者，焦虑抑郁，综合干预

    Abstract：Objective To explore the effect of comprehensive intervention on improving the quality of life and reducing the anxiety and depression in caregivers of Alzheimer's disease (AD) who were immersed in anxiety and depression.Methods A total of 56 caregivers were enrolled in the study.Results After 6 months of intervention ......