【摘 要】目的：观察重组牛碱性成纤维细胞生长因子(贝复新)联合地奈德乳膏治疗化妆品接触性皮炎的疗效。方法：在92例化妆品接触性皮炎患者中随机分出研究组47例和对照组45例。研究組采用重组牛碱性成纤维细胞生长因子联合地奈德乳膏治疗，对照组单纯外用地奈德乳膏治疗，对比观察两组的临床疗效。结果：2周后研究组有效率为93.6%，对照组为60%，两组存在显著性差异(P<0.01)。结论：重组牛碱性成纤维细胞生长因子针对化妆品接触性皮炎早期皮肤红肿、渗出，具有良好的治疗效果，可以快速修复皮肤受损屏障，地奈德乳膏待皮肤渗出消退后，隔日一次外涂，可极大缩短治疗周期，治疗期间持续应用重组牛碱性成纤维细胞生长因子，可提高皮肤的耐受性，对受损皮肤屏障具有良好的滋润保湿作用。

    【关键词】贝复新;化妆品接触性皮炎;疗效

    Abstract：Objective To observe the therapeutic effect of recombinant bovine basic fibroblast growth factor (Befuxin) combined with desonide cream on cosmetic contact dermatitis. Methods A total of 92 patients with cosmetic contact dermatitis were randomly divided into study group (47 cases) and control group (45 cases). The study group was treated with recombinant bovine basic fibroblast growth factor combined with dinide cream ......