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编号:12151932
Miles术与保肛术治疗直肠癌的疗效对比(1)
http://www.100md.com 2011年11月1日 郑宏伟
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     【摘要】目的 比较Miels术与保肛术治疗直肠癌的疗效,为临床提供参考。方法 选择我院2003年8月~2006年7月收治的直肠癌患者186例,其中对照组80例,行Miles术治疗;观察组106例,行保肛术治疗。观察并比较两组患者术后肿瘤复发率、转移率、五年生存率和生存质量的差异。结果 术后随访1年,对照组患者复发率为6.25%,远处转移率为13.75%,五年生存率为61.25%;观察组患者复发率为6.60%,远处转移率为13.21%,五年生存率为61.32%。两组患者术后肿瘤复发率、转移率和五年生存率比较,差异无统计学意义(p>0.05)。观察组患者生存质量评分明显高于对照组,差异有统计学意义(p<0.05)。结论 Miles术与保肛术治疗直肠癌的疗效相当,保肛术患者术后生存质量明显优于Miles术患者,在病情允许的情况下,临床应首选保肛术治疗直肠癌。

    【关键词】Miels术 保肛术 直肠癌 临床疗效

    中图分类号:R735.37文献标识码:A文章编号:1005-0515(2011)11-030-02

    Miles operation and the surgical treatment of rectal cancer compared the efficacy

    Zheng Hongwei

    (Xinmi City General Hospital, Zheng Coal Group, Xinmi, 452 371)

    【Abstract】Objective To compare Miels patients with rectal cancer treatment efficacy for clinical reference. Methods A hospital in August 2003 - July 2006 cancer patients admitted to 186 cases in which the control group 80 patients underwent Miles operation treatment; observation group, 106 patients underwent rectal surgery. Observe and compare the postoperative recurrence rate, metastasis rate, five-year survival rate and quality differences. Results The patients were followed up 1 year in the control group of patients relapse rate was 6.25%, distant metastasis rate was 13.75%, five-year survival rate was 61.25%; the observation group were recurrence rate was 6.60%, distant metastasis rate was 13.21%, five-year survival rate was 61.32%. Postoperative recurrence rate, metastasis rate and five-year survival rate, the difference was not statistically significant (p> 0.05). The patients quality of life score was significantly higher, the difference was statistically significant (p <0.05). Conclusion Miles patients with rectal cancer treatment as effective as surgery, rectal surgery patients after Miles operation was significantly better than the quality of life of patients, the condition permitting, should be the preferred clinical treatment of rectal cancer.

    【Keywords】Miels surgery rectal surgery cancer clinical efficacy

    直肠癌是临床常见的恶性肿瘤之一,目前的治疗方法包括放疗、化疗和手术等几种手段单独或联合应用。传统的Miles术一直以来都是治疗直肠癌的“金标准”,但由于腹部造口等原因给患者带来极大的生理和心理痛苦,导致生存质量下降[1]。近年来,保留直肠癌患者肛门括约肌功能的手术越来越广泛地应用于临床,受到广大患者的欢迎。我院对比了Miles术和保肛术治疗直肠癌的临床疗效,现将结果报告如下:

    1 资料与方法

    1.1 一般资料

    选择我院2003年8月~2006年7月收治的直肠癌患者186例 ......

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