[摘要] 目的 介绍CT或B超引导下碘125粒子永久植入治疗淋巴结转移或淋巴瘤所致淋巴结肿大的技术方法并评价其临床价值。方法 31例恶性肿瘤转移淋巴结，8例淋巴瘤行CT或B超引导下碘125粒子植入，依据植入前1周内CT图像应用计算机治疗计划系统制定粒子植入计划，按计划在CT或B超引导下穿刺植入碘125粒子，术后4～6个月内复查CT观察粒子分布及疗效。结果 根据疗效评价标准判定，完全缓解(CR)38.46%(15/39)；部分缓解(PR)48.71%(19/39)；无变化(AC)7.69%(3/39)；恶化(PD)5.12%(2/39)。总有效率(CR+PR)为87.18%(34/39)，未见严重并发症和治疗相关的放射损伤。 结论 碘125粒子永久植入治疗转移淋巴结及淋巴瘤是一种安全、可靠，疗效显著的治疗方法。

    [关键词] 碘125粒子； 放疗； 恶性淋巴结肿大； 安全性

    [中图分类号] R322.2+5[文献标识码] A[文章编号] 1005-0515(2011)-01-005-01

    [Abstract]Objective To introduce the clinical value of the treatment for lymphadenopathy due to m alignant metastatic carcinoma of lymph node or lymphoma using the method of implantation with I125 under the guidance of CT or ultrasonic. Methods According to the systemic implantation plant on the basis of the previous week CT records, 31 patients of m alignant lymph nodes and 8 patients of lymphoma were implanted I125 under the guidance of CT or ultrasonic. All the patients had CT-review four or six month after the surgery to observe I125-distribution and evaluate the effect. ResultAccording to the therapeutic effect and evaluative standard, 38.46%(15∕39) of them are completely remission, 48.71%(19/39) of them are partly remission , 7.69%(3/39) of them have no change and 5.12%(2/39) of them get degeneration. The total effect rate (CR+PR) is 87.18% (34/39) and no severe complication and no radiation injury happened during this process. ConclusionThe treatment for m alignant lymphadenovarix using the method of implantation with I125 is safe, reliable and effectively. ...... 婵″倹鐏夐幃銊ユ躬娴ｈ法鏁ら幍瀣簚缁涘绁︾憴鍫熸閺冪姵纭堕弻銉ф箙閹存牔绗呮潪钘夊弿閺傚浄绱濋崣顖濆厴閺勵垵顫﹂幖婊呭偍瀵洘鎼告径杈╂埂閳ユ粏娴嗛惍浣测偓婵撶礉鐠囬鍋ｉ崙璇茬潌楠炴洘娓舵稉瀣煙閻ㄥ嫧鈧粎鏁搁懘鎴犲閳ユ繃鍨ㄩ垾婊冨斧缂冩垿銆夐垾婵婎問闂傤喓鈧拷


闂勬劒绨張宥呭閸ｃ劌甯囬崝娑崇礉缂冩垹鐝柈銊ュ瀻娣団剝浼呴崣顏冪返閻栧崬绺炬导姘喅閹存牗婀佹稉鈧€规氨袧閸掑棛娈戝▔銊ュ斀娴兼艾鎲冲ù浣筋潔閵嗭拷
濮濓拷娣団剝浼�闂団偓鐟曪拷 1 缁夘垰鍨庨敍鍫濆帳鐠愯鏁為崘宀€娅ヨぐ鏇炴倵濮ｅ繐銇夐崣顖欎簰妫板棗褰�10娑擃亞袧閸掞拷閿涘鈧拷
    娣団剝浼呮禒鍛返閸欏倽鈧喛绱濇稉宥嗙€幋鎰崲娴ｆ洑绠ｅ楦款唴閵嗕焦甯归懡鎰灗閹稿洤绱╅妴鍌涙瀮缁旂姷澧楅弶鍐ㄧ潣娴滃骸甯拋妞剧稊閺夊啩姹夐敍宀冨閹劏顓绘稉鐑橆劃閺傚洣绗夌€规粏顫﹂弨璺虹秿娓氭稑銇囩€硅泛鍘ょ拹褰掓鐠囦紮绱濈拠鐑藉仏娴犺埖鍨ㄩ悽浣冪樈闁氨鐓￠幋鎴滄粦閿涘本鍨滄禒顒佹暪閸掍即鈧氨鐓￠崥搴礉娴兼氨鐝涢崡鍐茬殺閹劎娈戞担婊冩惂娴犲孩婀扮純鎴犵彲閸掔娀娅庨妴锟�

瀵邦喕淇婇弬鍥╃彿  閸忚櫕鏁為惂鐐  鐠囧嫯顔戦崙鐘插綖  閹兼粎鍌ㄩ弴鏉戭樋