[摘要] 目的 探讨肝纤维化血清学标志物水平与慢性乙肝患者肝纤维化的关系。方法 酶联免疫吸附法检测血清LN、HA及Ⅳ-C，与肝活检纤维化程度进行相关性分析。结果 LN、HA、Ⅳ-C随纤维化程度加重而升高，与纤维化程度显著相关(p均<0.05)。结论 血清LN、HA以及Ⅳ-C检测可准确反映慢性乙型肝炎患者的肝纤维化程度。

    [关键词] 慢性乙型肝炎； 血清学标志物； 纤维化

    [中图分类号] R512.6+2[文献标识码] B[文章编号] 1005-0515(2011)-07-023-01

    Chronic Hepatitis B Serological Markers in Patients with Liver Fibrosis

    [Abstract] Objective To investigate the serological markers of liver fibrosis with chronic hepatitis B patients the level of liver fibrosis. Methods Of serum enzyme-linked immunosorbent assay in LN, HA and Ⅳ-C, and liver biopsy fibrosis correlation analysis. Results Of LN, HA, Ⅳ-C and increased with increasing fibrosis, was significantly associated with fibrosis (p <0.05).

    慢性乙型病毒性肝炎所致肝损害可使肝脏星状细胞分泌细胞间质 ......