[摘要] 目的 观察小儿心脏病手术基础麻醉中阿托品与长托宁对腺体分泌、心率的影响。方法 60例先天性心脏病患儿随机双盲分为2组，阿托品0.01mg/kg(A组)、长托宁0.02mg/kg(B组)，分别与氯胺酮联合对患儿进行基础麻醉。记录小儿诱导和术中的心率及气管插管时口腔分泌物量。结果 两试验组口腔分泌物量无差异。A组诱导后至转机前心率下降，B组心率平稳。结论 小儿心脏手术运用0.02mg/kg长托宁和氯胺酮联合进行基础麻醉，既能够有效抑制唾液腺分泌，还可以保持术中心率平稳。

    [关键词] 长托宁； 基础麻醉； 先天性心脏病

    [中图分类号] R541[文献标识码] B[文章编号] 1005-0515(2011)-08-001-02

    The Different Efficacy of Penehyclidine Hydrochloride or Atropine Using in Pediatric Congenital Heart Disease Surgery

    [Abstract] Objective To evaluate efficacy of penehyclidine hydrochloride or atropine used in heart surgery foundation anesthesia.Methods 60 children who undergoing CHD surgery were randomly allocated into 2 groups.The children were medicated by intramuscularly injection with atropine 0.01 mg/kg(group A) or Penehyclidine hydrochloride 0.02 mg/kg(group B), combined with ketamine 7mg/kg when they were picked up into the operation room.The patients' heart rate(HR) and secretion of salivary gland were recorded during the process of the anesthetic induction and operation.Results The salivary secretion hadn't significant difference between 2 groups.The HR in group A significantly decreased from induction to the beginning of the ECC ......