干扰FLT3基因表达对急性骨髓系白血病细胞活性的影响(2)
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综上：1)siRNA干扰HL-60细胞FLT3基因表达可抑制细胞增殖，促进细胞凋亡。2)LY294002可以抑制细胞增殖，促进细胞凋亡；3)FLT3-shRNAi与LY294002联合作用可更有效地抑制细胞活性，促进细胞凋亡。这为RNAi以及RNAi联合治疗白血病提供了理论依据。
参考文献
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