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血管外膜脂肪组织分泌HIMF促进平滑肌细胞增殖(2)
http://www.100md.com 2012年2月1日 朱烨 张红明 王辉
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     HIMF为一种新发现的分泌蛋白,很可能是一种信号分子,然而,其究竟传递哪些生理及其病理信号,目前仍知之甚少,其在血液中分泌的浓度如何,分泌后是否能影响平滑肌细胞增殖,迁移,有待进一步阐明。

    参考文献

    [1] Falk E.Pathogenesis of atherosclerosis[J].1 J Am Coll Cardiol,2006,47(8Suppl):C7-12.

    [2] Elvire Henrichot,Cristiana E.Juge-Aubry; Production of Chemokines by Perivascular Adipose Tissue A Role in the Pathogenesis of Atherosclerosis?[J]. Arteriosclerosis,Thrombosis,and Vascular Biology,2005,25:2594.

    [3] 1Holcomb IN,Kabakoff RC,Chan B,et al.Baker TW,HIMF,a novel cysteine-rich secreted protein associated with pulmonary inflammation,defines a new gene family[J].EMBO J,2000,19(15):4046-4052.

    [4] Nair MG,Gallagher IJ,Taylor MD et al.Chitinase and Fizz family members are a generalized feature of nematode infection with selective upregulation of Ym1 and HIMF by antigen-presenting cells[J].Infect Immun,2005,73(1):385-394.

    [5] Teng X,Li D,Champion HC,Johns RA.HIMF/HIMFalpha,a novel hypoxia-induced mitogenic factor in lung with vasoconstrictive and angiogenic properties[J].Circ Res,2003,92(10):1065-1067.

    [6] Barandier C,Montani JP,Yang Z.Mature adipocytes and perivascular adipose tissue stimulate vascular smooth muscle cell proliferation: effects of aging and obesity[J].Am J Physiol Heart Circ Physiol,2005,289(5):H1807-13.

    [7] Verlohren S,Dubrovska G,Tsang SY etal.Visceral periadventitial adipose tissue regulates arterial tone of mesenteric arteries[J].Hypertension.2004,44(3):271-6.

    [8] Liu T,Dhanasekaran SM,Jin H et al.HIMF stimulation of myofibroblast differentiation[J].Am J Pathol,2004,164(4):1315-1326.

    [9] Li D,Fernandez LG,Dodd-o J et al.Upregulation of hypoxia-induced mitogenic factor in compensatory lung growth after pneumonectomy[J].Am J Respir Cell Mol Biol,2005,32(3):185-191.

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