medium- and low-dose groups， and Radix Hedysari saponin medium- and low-dose groups decreased obviously. Conclusion Polysaccharide， flavone and saponin of Radix Hedysari have the abilities to alleviate inflammation of pulmonary alveoli， inhibit proliferation and deposition of collagen fibrils， and reduce the contents of HA and LA in lung tissue. Among these active ingredients， flavone has the best effect.

    Key words： pulmonary fibrosis； active ingredients in Radix Hedysari； collagen area； HA； LN； rats

    肺纤维化病理改变以大量的成纤维细胞聚集、细胞外基质沉积并伴有炎症和损伤所致组织结构破坏为特征 ......