补肾健脾方对人结肠癌移植瘤生长及血清血管内皮生长因子和基质金属蛋白酶7表达的影响(3)
综上,补肾健脾方能抑制裸鼠皮下移植瘤的生长,延长荷瘤鼠的生存时间,其机制可能与下调VEGF和MMP-7表达有关。
参考文献:
[1] TAN K Y, LIU C B, CHEN A H, et al. The role of traditional Chinese medicine in colorectal cancer treatment[J]. Tech Coloproctol, 2008,12(1):1-6.
[2] CHANG K H, BRODIE R, CHOONG M A, et al. Complementary and alternative medicine use in oncology:a questionnaire survey of patients and health care professionals[J]. BMC Cancer,2011,11:196.
[3] 张彦博,刘宣,季青,等.健脾解毒方联合化疗治疗转移性结直肠癌临床研究[J].中华中医药杂志,2015,30(6):2090-2093.
[4] FOLKMAN J. Clinical applications of research on angiogenesis:seminars in medicine of the Beth Israel Hospital[J]. N Engl J Med,1995,333(26):1757.
[5] THOMPSON W D,LIW W,MARAGOUDAKIS M. The clinical manipulation of angiogenesis:pathology, side-effects, surprises, and opportunities with novel human therapies[J]. J Pathol,2000, 190(3):330.
[6] KAWASAKI T, NOSHO K, OHNISHI M, et al. Correlation of beta- catenin localization with cyclooxygenase-2 expression and CpG island methylator phenotype (CIMP) in colorectal cancer[J]. Neoplasia,2007,9(7):569.
[7] 鄧立春,沈伟生,张瑶,等.化疗对晚期结直肠癌患者血清VEGF水平的影响[J].实用临床医药杂志,2010,14(3):90-93.
(收稿日期:2017-10-11)
(修回日期:2017-11-26;编辑:华强), http://www.100md.com(王元惠 冯媛媛 韩植芬)
参考文献:
[1] TAN K Y, LIU C B, CHEN A H, et al. The role of traditional Chinese medicine in colorectal cancer treatment[J]. Tech Coloproctol, 2008,12(1):1-6.
[2] CHANG K H, BRODIE R, CHOONG M A, et al. Complementary and alternative medicine use in oncology:a questionnaire survey of patients and health care professionals[J]. BMC Cancer,2011,11:196.
[3] 张彦博,刘宣,季青,等.健脾解毒方联合化疗治疗转移性结直肠癌临床研究[J].中华中医药杂志,2015,30(6):2090-2093.
[4] FOLKMAN J. Clinical applications of research on angiogenesis:seminars in medicine of the Beth Israel Hospital[J]. N Engl J Med,1995,333(26):1757.
[5] THOMPSON W D,LIW W,MARAGOUDAKIS M. The clinical manipulation of angiogenesis:pathology, side-effects, surprises, and opportunities with novel human therapies[J]. J Pathol,2000, 190(3):330.
[6] KAWASAKI T, NOSHO K, OHNISHI M, et al. Correlation of beta- catenin localization with cyclooxygenase-2 expression and CpG island methylator phenotype (CIMP) in colorectal cancer[J]. Neoplasia,2007,9(7):569.
[7] 鄧立春,沈伟生,张瑶,等.化疗对晚期结直肠癌患者血清VEGF水平的影响[J].实用临床医药杂志,2010,14(3):90-93.
(收稿日期:2017-10-11)
(修回日期:2017-11-26;编辑:华强), http://www.100md.com(王元惠 冯媛媛 韩植芬)