关键词:高危型人乳头瘤病毒;宫颈病变;中医体质;年龄;p16抑癌蛋白;表达强度
, 百拇医药
中图分类号:R271.913 文献标识码:A 文章编号:1005-5304(2020)01-0014-05
DOI:10.3969/j.issn.1005-5304.201908251
Discussion on Physical Characteristics of Cervical Lesions Patients with High-riskHuman Papillomavirus Infection
LIU Jun, XUE Xiaoou, MA Xiuli, LI Yanhua
Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, China
Abstract: Objective To explore the characteristics of TCM constitution distribution in cervical lesions patients with high-risk human papillomavirus (HR-HPV) infection; To analyze the relationship between clinical characteristics and constitutional types; To provide evidence for the prevention and treatment of cervical lesions caused by HR-HPV infection in TCM. Methods Epidemiological methods was used; 135 cases of cervical lesions with HR-HPV infection were collected by questionnaire survey; their constitution distribution characteristics and the relationship between the main constitution types and the grade of cervical lesions, the characteristics of HR-HPV infection, age and the expression intensity of p16 anti-cancer protein were analyzed. Results The constitutional types of cervical lesions patients infected with HR-HPV were damp-heat, yang-deficiency, peace, qi-deficiency, qi-depression, yin-deficiency, phlegm-dampness, blood stasis and specific endowment in order from high to low, with statistical significance (P<0.05). The degree of cervical lesions, the characteristics of HR-HPV infection, age and the expression of p16 anti-cancer protein of patients with different constitution were different, with statistical significance (P<0.05). Conclusion The constitutional types of cervical lesions infected by HR-HPV are mainly damp-heat and yang deficiency, which are related to the degree of cervical lesions, HR-HPV infection characteristics, age, and p16 anti-cancer protein expression intensity., 百拇医药(刘君 薛晓鸥 马秀丽 李艳华)