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     【摘 要】 目的 了解Ⅱ型糖尿病(T2DM)患者无症状性心肌缺血(SMI)的发病情况，探讨与其相关的主要危险因素。方法 217例无心绞痛(或与心绞痛等同症状)的T2DM患者，根据心电图(静息、动态或负荷试验)诊断有无心肌缺血分为两组，对比观察心肌缺血与临床一股情况及各生化指标的相关性。结果 T2DM患者SMI发病率20.7%，其中女性与男性之比为3∶2，SMI组中年龄、血压、BMI、2hPG、HbAlc、TG、TC、LDL-C均高于对照组，而HDL-C低于对照组，且SMI组中吸烟者所占比例亦高于对照组。结论 T2DM患者中多种危险因子的集簇增加了心血管病变发生的机率，且女性患者心肌缺血的比例超过男性，提示对女性T2DM患者加强控制心血管危险因子的干预甚至比男性更重要。

    【关键词】 糖尿病；危险因素；并发症

    【Abstract】ObjectiveTo investigate the occurrence of silent myocardial ischemia (SMI) of the Type II diabetes mellitus (T2DM) patients and the related main risk factors.Methods 217 T2DM patients with silent myocardial ischemia (or same symptoms with angina) were divided into two groups,with or without myocardial ischemia according to the ECG (rest, dynamic or loading test) diagnosis to observe the correlativity between myocardial ischemia and the clinical manifestation as well as the biochemical indexes.ResultsSMI occurrence in T2DM patients was 20.7% and the ration of female to male was 3:2.The age,blood pressure,BMI,2hPG,HbAlc,TG and LDL-C were higher in the SMI group than in the control group.HDL-C in the SMI group was lower than that in the control group.The proportion of smokers in the SMI group was higher than the control group.ConclusionThe coexisting multiple risk factors in T2DM patients increase the chance of occurrence of cardiovascular diseases.The chance of occurrence of the cardiovascular diseases in female patients surpasses the male patients,indicating it is more important for the female patients to strengthen the intervention for the cardiovascular diseases. ......