【摘 要】 目的 早期及时的诊断和正确的治疗创伤导致的弥漫性血管内凝血 (DIC),以减少误诊及死亡率,提高治愈率。方法 回顾性研究我院骨科2005～2007年内创伤导致的DIC 4例患者的一般状况及其基础疾病、诊断和治疗、转归情况。结果 创伤导致的DIC,主要是与创伤后血容量不足,大量的凝血因子丢失有关。4例患者均得到早期良好的治疗,其成功率为100%。结论 创伤导致的DIC一经确诊就要尽早治疗,早期治疗可以明显降低死亡率,提高治愈率,治疗关键是祛除原发病,按照缺什么补什么的原则并给予肝素化治疗。晚期以纤溶为主,有严重出血倾向,方可抗纤溶治疗。

    【关键词】 创伤;DIC诊断;肝素治疗;血小板;抗纤溶

    【Abstract】 Objective To improve the early diagnosis and treatment of DIC caused by trauma,so as to reduce misdiagnosis and death rate, and raise recovery rate. Methods Data of four cases of DIC caused by trauma in department of osteology from 2005 to 2007 including general condition and basic disease, diagnosis and treatment, prognosis etc. were studied retrospectively. Results DIC caused by trauma was related to hypovolemia after trauma and a lot of blood coagulation factors loosing. Four patients was received early favorable treatment with a successful rate of 100%.Conclusion DIC caused by trauma should be treated as soon as possible. Early treatment can obviously reduce death rate and improve recovery rate. The key point of treatment is to eliminate primary disease and implement heparin therapy according to the principle of "supplementing what is deficient". Fibrinolysis is the main therapy in advanced stage.Antiplasmin may be used only for patients with hemorrhagic tendency. ......