五味子多糖的抗突变作用研究
摘 要 目的:研究五味子多糖对环磷酰胺(CP)致小鼠微核率、染色体畸变率改变的影响,以探讨其对突变的拮抗作用。方法:50只小鼠随机分成5组,连续7 d给予不同剂量的五味子多糖,于第8天给予环磷酰胺,之后取骨髓常规制片,光学显微镜观察计数微核和染色体个数。结果:五味子多糖可抑制微核率;还可降低染色体畸变率。结论:五味子多糖具抗突变作用。关键词 五味子多糖 抗突变 微核 染色体
中图分类号:R286
文献标识码:A
文章编号:1006-1533(2007)10-0462-02
A study on anti-mutation effect of Schisandra Chinensis polysaccharide
Chen Wenjing,Wang Yanjie,Ji Yubin
(Life Science and Enviromental Science Research Center of Haerbin Commercial University,Haerbin 150076)
ABSTRACT Objective: To study the influence of Schisandra Chinensis polysaccharide on changes in micronucleus frequencies and chromosome aberration rate induced by cyclophosphamide in mice ......
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