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[16] Tonnel AB， Perez T， Grosbois JM， et al. Effect of tiotropium on health-related quality of life as a primary efficacy endpoint in COPD [J]. Int J Chron Obstruct Pulmon Dis， 2008， 3(2)： 301-310.[17] Casaburi R， Mahler DA， Jones PW， et al. A long-term evaluation of once-daily inhaled tiotropium in chronic obstructive pulmonary disease [J]. Eur Respir J ......
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