抗癫痫新药

    章悦*朱国行**

    (复旦大学附属华山医院神经内科 上海 200040)

    摘 要传统抗癫痫药物尽管有效且价廉，但仍有部分癫痫患者的癫痫发作不能得到有效控制或者不能耐受药物的不良反应，因此需要研发新的抗癫痫药物。总的来说，抗癫痫新药的不良反应较小、药物相互作用较少，临床使用方便，不过也需要注意每种新药的特点，以免错误使用。本文介绍近20年间国内、外上市的10余种抗癫痫新药。

    关键词癫痫 抗癫痫药物 新药

    New anti-epilepsy drugs

    ZHANG Yue*, ZHU Guoxing**

    (Department of Neurology, Huashan Hospital, Fudan University, Shanghai 200040, China)

    ABSTRACTAlthough traditional anti-epilepsy drugs are effective and economic, some patients still have poor control of seizures or can not tolerate drug side-effects. Thus new anti-epilepsy drugs have been continuously developed. Generally speaking, new anti-epilepsy drugs are easy to use because they have better tolerability than traditional ones and can minimize drug interactions. However, the characteristic of each medicine differs. Herein we introduce more than 10 new anti-epilepsy drugs which have been sold in domestic or abroad market.

    KEY WORDSepilepsy; anti-epilepsy drugs; new drugs

    近20年间，国内、外陆续上市了10多种抗癫痫新药，本文简要介绍如下。

    1 国内上市的新药

    1.1 加巴喷丁

    加巴喷丁是美国Warner-Lanbert公司开发的一个抗癫痫药 ......