突发性耳聋120例疗效与预后的影响因素分析(1)
摘 要 目的：探讨相关因素对突发性耳聋疗效及预后的影响，为临床治疗提供参考。方法：应用Logistic回归分析120例突发性耳聋病例资料，对性别、年龄、病程、听力损失程度、听力曲线类型、就诊是否伴有耳聋眩晕等多种因素进行筛选，获得临床上与突发性耳聋效疗及预后相关的因素。结果：120例中治愈41例，显效及有效57例，总有效率为81.7%。结果发现，患者的年龄(OR=1.223)、初诊病程(OR=1.556)，治疗前耳聋程度(OR=6.225)、听力曲线类型(OR=6.247)、伴有耳鸣(OR=6.238)及伴有眩晕(OR=5.322)均与疗效、预后相关(P<0.05)；性别、患耳部位与疗效无明显相关性(P>0.05)。结论：突聋患者年龄越小、病程越短，其疗效和预后越好；听力损失程度越高、听力曲线为全聋型及伴有耳鸣眩晕预后越差。
关键词 突发性耳聋 疗效 预后 因素分析
中图分类号：R764.437 文献标识码：A 文章编号：1006-1533(2016)05-0045-04
The logistic regression analysis of the influencing factors on the effects and prognosis of 120 cases of patients with sudden deafness
LU Jun1*， HONG Huimin2， SHEN Wei3**(1. Sinopharm Lingyun Biological Pharmaceutical (Shanghai) Co. Ltd.， Shanghai 200002，China； 2. Sinopharm Group Co. Ltd.， Shanghai
200051， China； 3. Putuo Hospital affiliated to Shanghai University of Traditional Chinese Medicine， Shanghai 200062， China)
ABSTRACT Objective： To investigate the effects of related factors on the effectiveness and prognosis of sudden deafness so as to provide a reference for its clinical treatment. Methods： The data of 120 cases of patients with sudden deafness were analyzed by logistic regression and the various factors including gender， age， duration， degree of hearing loss， hearing curve type， with or without tinnitus and dizziness were screened so as to obtain the factors associated with the efficacy and prognosis in the clinical treatment of sudden deafness. Results： Forty-one cases were cured and fifty-seven cases were excellent and effective recovery in 120 cases. The total effective rate reached 81.7%. The results showed that efficacy and prognosis were associated with age (OR=1.223)， newly diagnosed disease duration (OR=1.556)， the extent of pre-treatment of deafness (OR=6.225)， hearing curve type (OR=6.247)， with tinnitus (OR=6.238) and dizziness (OR=5.332) (P<0.05) while the efficacy was not associated with gender and parts of the affected ear (P>0.05). Conclusion： The younger the patients with sudden deafness and the shorter duration， the better the efficacy and prognosis are； the higher the degree of hearing loss and hearing curve with deaf and tinnitus and dizziness， the worse the prognosis of the patients would be.
KEY WORDS sudden deafness； efficacy； prognosis； factor analysis
突发性耳聋(sudden deafness or sudden sensorineural hearing loss)是耳鼻咽喉科常见急症，是指突然发生的、病因不明的感音神经性耳聋，可伴耳鸣及眩晕[1]。突发性耳聋病理生理改变复杂，没有明确的致病因素，目前临床治疗上常采用激素、改善微循环、扩张血管、抗病毒、高压氧等方法综合治疗[2]。近年来，突发性耳聋发病率有上升及低龄化的趋势，已受到耳科专家的广泛关注。突发性耳聋严重影响生活质量，各种因素对疗效及预后的影响尚无定论。本文通过分析120例突发性耳聋患者资料，探讨相关影响因素的作用，为临床治疗及预后判断提供依据。, http://www.100md.com(陆俊 洪惠敏 沈伟)
关键词 突发性耳聋 疗效 预后 因素分析
中图分类号：R764.437 文献标识码：A 文章编号：1006-1533(2016)05-0045-04
The logistic regression analysis of the influencing factors on the effects and prognosis of 120 cases of patients with sudden deafness
LU Jun1*， HONG Huimin2， SHEN Wei3**(1. Sinopharm Lingyun Biological Pharmaceutical (Shanghai) Co. Ltd.， Shanghai 200002，China； 2. Sinopharm Group Co. Ltd.， Shanghai
200051， China； 3. Putuo Hospital affiliated to Shanghai University of Traditional Chinese Medicine， Shanghai 200062， China)
ABSTRACT Objective： To investigate the effects of related factors on the effectiveness and prognosis of sudden deafness so as to provide a reference for its clinical treatment. Methods： The data of 120 cases of patients with sudden deafness were analyzed by logistic regression and the various factors including gender， age， duration， degree of hearing loss， hearing curve type， with or without tinnitus and dizziness were screened so as to obtain the factors associated with the efficacy and prognosis in the clinical treatment of sudden deafness. Results： Forty-one cases were cured and fifty-seven cases were excellent and effective recovery in 120 cases. The total effective rate reached 81.7%. The results showed that efficacy and prognosis were associated with age (OR=1.223)， newly diagnosed disease duration (OR=1.556)， the extent of pre-treatment of deafness (OR=6.225)， hearing curve type (OR=6.247)， with tinnitus (OR=6.238) and dizziness (OR=5.332) (P<0.05) while the efficacy was not associated with gender and parts of the affected ear (P>0.05). Conclusion： The younger the patients with sudden deafness and the shorter duration， the better the efficacy and prognosis are； the higher the degree of hearing loss and hearing curve with deaf and tinnitus and dizziness， the worse the prognosis of the patients would be.
KEY WORDS sudden deafness； efficacy； prognosis； factor analysis
突发性耳聋(sudden deafness or sudden sensorineural hearing loss)是耳鼻咽喉科常见急症，是指突然发生的、病因不明的感音神经性耳聋，可伴耳鸣及眩晕[1]。突发性耳聋病理生理改变复杂，没有明确的致病因素，目前临床治疗上常采用激素、改善微循环、扩张血管、抗病毒、高压氧等方法综合治疗[2]。近年来，突发性耳聋发病率有上升及低龄化的趋势，已受到耳科专家的广泛关注。突发性耳聋严重影响生活质量，各种因素对疗效及预后的影响尚无定论。本文通过分析120例突发性耳聋患者资料，探讨相关影响因素的作用，为临床治疗及预后判断提供依据。, http://www.100md.com(陆俊 洪惠敏 沈伟)