治疗急性髓系白血病/高危骨髓增生异常综合征新药:新型Hedgehog信号通路抑制剂glasdegib
[9] Briscoe J, Therond PP. The mechanisms of Hedgehog signalling and its roles in development and disease[J]. Nat Rev Mol Cell Biol, 2013, 14(7): 416-429.[10] Martinelli G, Oehler VG, Papayannidis C, et al. Treatment with PF-04449913, an oral Smoothened antagonist, in patients with myeloid malignancies: a phase 1 safety and pharmacokinetics study[J]. Lancet Haematol ......
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