艾地苯醌联合丁苯酞注射液治疗进展性脑梗死的临床疗效观察
蔡双摘 要 目的:探讨艾地苯醌聯合丁苯酞注射液治疗进展性脑梗死的临床疗效。方法:纳入2019年1月—2020年12月江西省宜春市人民医院接诊的进展性脑梗死患者82例。按照随机数字表对照法分为两组,每组41例。对照组给予艾地苯醌治疗,30 mg/次,3次/d。观察组在对照组基础上联合丁苯酞静脉滴注100 mL,2次/d。两组均治疗10 d。观察美国国立卫生院卒中量表(NIHSS)评分、Barthel指数、修正Rankin量表(mRS)评分、凝血功能、疗效和不良反应发生情况。结果:观察组干预后NIHSS评分、mRS评分均低于干预前和对照组(P<0.05),Barthel指数则高于干预前和对照组(P<0.05)。观察组干预后凝血酶原时间(prothrombin time,PT)、部分凝血活酶时间(activated partial thromboplastin time,APTT)和凝血酶时间(thrombin time,TT)均高于干预前和对照组(P<0.05)。观察组治疗总有效率为95.12%,高于对照组的65.85%(P<0.05)。观察组和对照组不良反应发生情况对比,差异无统计学意义(P>0.05)。结论:艾地苯醌联合丁苯酞注射液治疗进展性脑梗死效果较好,能够较好地改善患者NIHSS评分、Barthel指数、mRS评分及凝血功能,提高治疗效果,且不增加不良反应。
关键词 进展性脑梗死;艾地苯醌;丁苯酞注射液;临床疗效
中图分类号:R743 文献标志码:A 文章编号:1006-1533(2021)24-0037-03
Observation of the clinical efficacy of idebenone combined with butylphthalide injection in the treatment of progressive cerebral infarction
CAI Shuang
(Emergency Medicine Department of Yichun People’s Hospital, Yichun, Jiangxi 336000, China)
ABSTRACT Objective: To investigate the clinical efficacy of idebenone combined with butylphthalide injection in the treatment of progressive cerebral infarction. Methods: Eighty-two patients with progressive cerebral infarction received by Yichun People’s Hospital of Jiangxi Province from January 2019 to December 2020 were included. According to the random number table control method ......
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