摘 要 几丁质酶-3样蛋白-1(chitinase-3 like protein-1，CHI3L1)是一种与炎症反应相关的蛋白质，研究发现其参与多种炎症性疾病、肿瘤和神经退行性疾病的病理生理过程，在这些疾病的诊断和治疗中具有一定的研究价值和前景。本文回顾CHI3L1与多种疾病发生和发展的关系。

    关键词 炎症标志物；几丁质酶-3样蛋白-1；肿瘤；神经退行性疾病

    中图分类号：R587.1 文献标志码：A 文章编号：1006-1533(2024)22-0027-03

    引用本文 王娜娜. 几丁质酶-3样蛋白-1：一种血清炎症标志物[J]. 上海医药， 2024， 45(22)： 27-29； 43.

    Chitinase-3-like protein-1 - A Serum inflammatory markers

    WANG Nana

    (General Practice Department of Hongmei Community Health Service Center of Xuhui District， Shanghai 200233， China)

    ABSTRACT Chitinase-3-like protein-1(CHI3L1) is a protein associated with inflammatory responses， the research finds it participates in the pathophysiological processes of various inflammatory diseases， cancers， and neurodegenerative diseases， and it holds significant research value and prospects in the diagnosis and treatment of these conditions. This article reviews the relationship between CHI3L1 and the onset and progression of multiple diseases.

    KEY WORDS inflammatory marker； Chitinase-3-like protein-1； tumor； neurodegenerative disease

    几丁质酶-3样蛋白-1(chitinase-3 like protein-1 ......