VEGF基因表达的转录调控机制研究进展(2)
[3]Rak J,Mitsuhashi Y,Sheehan C,et al.Oncogenes and tumor angiogenesis:differential modes of vascular endothelial growth factor up-regulation in ras-transformed epithelial cells and fibroblasts,2000,60:490-498.
[4]Shafee N,Kaluz S,Ru N,et al.PI3K/Akt activity has variable cell-specific effects on expression of HIF target genes,CA9 and VEGF,in human cancer cell lines.Cancer Letters,2009,282:109-115.
[5]Laughner E,Taghavi P,Chiles K,et al.HER2(neu) signaling increases the rate of hypoxia-inducible factor 1 alpha (HIF-1 alpha) synthesis:novel mechanism for HIF-1 mediated vascular endothelial growth factor expression. Mol Cell Biol,2001,21:3995-4004.
[6]Minet E,Michel G,Mottet D,et al.c-JUN gene induction and AP-1 activity is regulated by a JNK-dependent pathway in hypoxic HepG2 cells.Exp Cell Res,2001,265(1):114-124.
[7]Mukhopadhyay D,Knebelmann B,Cohen HT,et al.The von Heppel-Lindau tumor suppressor gene product interacts with Sp1 to repress vascular endothelial growth factor promoter activity.Mol Cell Biol,1997,17:5629-39.
[8]Curry JM,Eubank TD,Roberts RD,et al.M-CSF Signals through the MAPK/ERK Patheway via Sp1 to Induce VEGF Production and Induces Angiogenesis In Vivo.Plos one,2008,3(10):e3405.
[9]Berra E,Milanini J,Richard DE,et al.Signaling Angiogenesis via p42/p44 MAP Kinase and Hypoxia,Biochem Pharmacol,2000,60(8):1171-8.
[10]Clifford SC,Maher ER.Von Hippel-Lindau disease:clinical and molecular perspectives.Adv Cancer Res,2001,82:85-105., 百拇医药(刘 扬 周宇政 李日涵)
[4]Shafee N,Kaluz S,Ru N,et al.PI3K/Akt activity has variable cell-specific effects on expression of HIF target genes,CA9 and VEGF,in human cancer cell lines.Cancer Letters,2009,282:109-115.
[5]Laughner E,Taghavi P,Chiles K,et al.HER2(neu) signaling increases the rate of hypoxia-inducible factor 1 alpha (HIF-1 alpha) synthesis:novel mechanism for HIF-1 mediated vascular endothelial growth factor expression. Mol Cell Biol,2001,21:3995-4004.
[6]Minet E,Michel G,Mottet D,et al.c-JUN gene induction and AP-1 activity is regulated by a JNK-dependent pathway in hypoxic HepG2 cells.Exp Cell Res,2001,265(1):114-124.
[7]Mukhopadhyay D,Knebelmann B,Cohen HT,et al.The von Heppel-Lindau tumor suppressor gene product interacts with Sp1 to repress vascular endothelial growth factor promoter activity.Mol Cell Biol,1997,17:5629-39.
[8]Curry JM,Eubank TD,Roberts RD,et al.M-CSF Signals through the MAPK/ERK Patheway via Sp1 to Induce VEGF Production and Induces Angiogenesis In Vivo.Plos one,2008,3(10):e3405.
[9]Berra E,Milanini J,Richard DE,et al.Signaling Angiogenesis via p42/p44 MAP Kinase and Hypoxia,Biochem Pharmacol,2000,60(8):1171-8.
[10]Clifford SC,Maher ER.Von Hippel-Lindau disease:clinical and molecular perspectives.Adv Cancer Res,2001,82:85-105., 百拇医药(刘 扬 周宇政 李日涵)