EBV\HBV感染与鼻咽癌远处转移的关系
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摘要:目的 研究EBV、HBV感染与鼻咽癌远处转移的关系。方法 收集经证实出现远处转移的55例鼻咽癌患者作为观察组,收集化疗后无瘤生存>6年的55例鼻咽癌患者作为参考组,对比两组患者乙肝两对半、EBV抗体检测结果。结果 观察组患者EBV-VCA-IgA抗体阳性率高于参考组,有统计学意义(P<0.05);观察组患者EA-IgA阳性率、感染率及EA-IgA抗体≥1:40率大于参考组,具有统计学意义(P<0.05);观察组患者e抗原、大三阳比例亦高于参考组,比较有统计学意义(P<0.05)。结论 相较无远处转移患者,鼻咽癌远处转移患者EBV及HBV感染更活跃,在一定程度上可揭示鼻咽癌远处转移风险。
关键词:EBV;HBV;鼻咽癌;远处转移
The Relationship between HBV ,EBV Infection and the Distant Metastasis of Nasopharyngeal Carcinoma
LIU Wen-ji
(Chenzhou City First People's Hospital,Chenzhou 423000,Hunan,China)
Abstract:ObjectiveTo study the EBV, relationship between HBV infection and distant metastasis of nasopharyngeal carcinoma (NPC). MethodsTo collect proved a distant metastasis of 55 cases of nasopharyngeal carcinoma patients as observation group, collect disease-free survival > 6 years after the chemotherapy of 55 patients with nasopharyngeal carcinoma as the reference group, compared two groups of patients' second liver two half-and-half, EBV antibody test results. ResultsObservation group of patients with EBV - VCA - IgA antibody positive rate is higher than the reference group, with statistical significance (P< 0 ......
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