恶性肿瘤再程放疗的疗效观察(1)
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摘要：目的 观察恶性肿瘤再程放疗的疗效。方法 回顾性分析29例接受再程放疗的患者，其中食管癌15例，鼻咽癌5例，椎体转移癌3例，宫颈癌、直肠癌、鼻腔NK/T细胞淋巴瘤、脑转移癌、髓母细胞瘤和脑胶质瘤各1例，肿瘤靶区剂量30～50Gy/10～25f。结果 对存在可评价病灶者，在放疗结束后取得完全缓解(CR)者为38.5%(10例/26例)，部分缓解(PR)为46.2%(12例/26例)， 1例(3.8%)稳定(SD)，2例(7.7%)PD，1人未评估。无进展生存期为4～36个月，中位时间8个月，1年的无进展生存率(PFS)为65%。严重的急性和晚期放射反应发生率分别为6.9%。结论 再程放疗安全、有效。
关键词：恶性肿瘤；再程放疗
中图分类号:R246.5 文献标识码:B
Effectiveness of Re-irradiation for Patients with M alignant Tumor
SONG Geng，HONG Yan-yan，CHEN Huai-dong，LI Chao，CHEN Zhen-dong
(Department of Oncology, The Second Affiliated Hospital of Anhui Medical University，Hefei 230601,Anhui,China)
Abstract：ObjectiveTo observe the effectiveness of re-irradiation for m alignant tumor.Methods29 paitents with m alignant tumor re-irradiated were enrolled,in whom 15 patients with esophageal cancer,5 with nasopharyngeal cancer,3 with spinal bone metastases,one with rectal cancer,one with cervical cancer,one with NK/T lymphoma in nasal cavity,one with metastatic brain tumor,one with medulloblastoma and one with cerebral glioma ......
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