摘要：目的 比较生理盐水和肝素对PICC封管的效果。方法 随机选取PICC置管的长期输液患者60例，分为观察组和对照组，每组30例。观察组用20ml生理盐水连续脉冲冲管；对照组采用1u/ml肝素稀释液脉冲冲管。比较两组患者堵管率及血凝指标：凝血酶原时间(PT)、活化部分凝血活酶时间(APTT)。结果 两组患者发生堵管均为2例，而观察组患者PT及APTT较对照组明显降低(P<0.05)。结论 生理盐水脉冲式封管在PICC置管时应用具有方便、性价比高、无风险等优点，值得推广。

    关键词：脉冲式封管；PICC

    Clinical Nursing Research Saline Pulsed Sealing Security Sealed Tube at PICC

    CHENG Jing-jing，CHEN Yan

    (Hefei Third Clinical College，Third People's Hospital of Hefei，Anhui Medical University，Hefei 230000，Anhui，China)

    Abstract：Objective To compare the normal saline and heparin on PICC sealed tube effect.Methods 60 cases were randomly selected patients with long-term infusion of PICC ......