冠心病患者血清γ—谷氨酰转移酶水平及临床意义分析(1)
摘要:目的 探讨血清γ-谷氨酰转移酶(GGT)水平与冠心病患者病情之间的关系以及临床意义。方法 择取本院于收治的冠心病患者207例,根据患者病变的严重程度,划分为单支病变组(95例)、双支病变组(63例)、三支病变组(49例),并择取同期收治的排除冠心病的患者52例作为对照组。对所有患者均行血清FINS、LDL-C、HDL-C、TG、TC、Glu、TBil、GGT检查。结果 冠心病组患者的FINS、LDL-C、TG、TC、Glu、GGT水平明显高于对照组患者,而冠心病组患者的HDL-C、TBil水平明显低于对照组患者,P<0.05;而且冠心病患者病变越严重,血清GGT水平越高,随之LDL-C、FINS水平也会大幅度提升,但TBil水平将会明显降低。结论 血清GGT水平与冠心病发生、发展之间存在密切联系,可以作为冠心病临床实验诊断的判定指标。
关键词:冠心病;血清-谷氨酰转移酶;临床意义
Clinical Significance of Serum γ-Valley Level in Patients with Coronary Heart Disease
, 百拇医药
HUANG Rong-ning,TAN Xiao-ming,WANG Zheng-dong,LI Zu-gao,FAN Shao-yong,LIANG Jian-hua
(Yulin First People's Hospital,Yulin 537000,Guangxi,China)
Abstract:Objective To investigate the serum levels of gamma glutamine transferase (GGT)level and coronary heart disease patients as well as the relationship between clinical significance.Methods In 207 cases of coronary heart disease (CHD)patients treated at our hospital will pick,according to the severity of the patients with lesions,is divided into single lesion group (95 cases),the double branch lesion group (63 cases),three lesion group(49 cases),and the hospital at the same time will pick out of 52 cases of coronary heart disease patients as control group.For all patients serum FINS,LDL-C,TG,TC,hdl-c leel,Glu,TBil,GGT inspection.Results The patients with coronary heart disease group of FINS,LDL-C,TG,TC,Glu,GGT level is significantly higher than the control group patients,and patients with coronary heart disease group of HDL-C,TBil level significantly lower than the control group patients,P<0.05;And coronary heart disease (CHD)patients with the disease is severe,the higher the level of serum GGT,LDL-C accordingly,FINS will also greatly enhance the level,but will significantly reduce TBil level.Conclusion Serum GGT level and coronary heart disease (CHD) there is close relationship between occurrence,development,and can judge index as a clinical laboratory diagnosis of coronary artery disease.
, 百拇医药
Key words:Coronary heart disease;Serum - glutamine transferase;Clinical significance
在冠心病危险因素方面的报道多集中于血脂、血糖、血压、C-反应蛋白、胆红素、年龄等,但国外相关文献指出,血清γ-谷氨酰转移酶(GGT)水平的变化,可以对心血管疾病进行预示[1]。基于此,笔者进了如下实验探讨:
1 资料与方法
1.1一般资料 择取本院于2014年1月~2016年6月收治的冠心病患者207例,所有患者均经过冠脉造影检查,确保符合冠心病诊断标准,并择取同期收治的排除冠心病的患者52例作为对照组,所有患者均不存在急性脑血管意外、肝肾功能障碍、血液病、恶性肿瘤、酗酒等情况,均享有本次实验的知情权,符合医学伦理学意义要求。207例冠心病患者中,男121例,女86例,平均年龄为(70.6±10.5)岁;根据患者病变的严重程度,划分为单支病变组(95例)、双支病变组(63例)、三支病变组(49例)。对照组患者中,男30例,女22例,平均年龄为(67.6±8.9)岁。比较四组患者的一般资料,相应数据组间不存在满足统计学意义要求的差异,即P>0.05。, 百拇医药(黄荣宁 谭晓明 王正东 黎祖高 樊少勇 梁建华)
关键词:冠心病;血清-谷氨酰转移酶;临床意义
Clinical Significance of Serum γ-Valley Level in Patients with Coronary Heart Disease
, 百拇医药
HUANG Rong-ning,TAN Xiao-ming,WANG Zheng-dong,LI Zu-gao,FAN Shao-yong,LIANG Jian-hua
(Yulin First People's Hospital,Yulin 537000,Guangxi,China)
Abstract:Objective To investigate the serum levels of gamma glutamine transferase (GGT)level and coronary heart disease patients as well as the relationship between clinical significance.Methods In 207 cases of coronary heart disease (CHD)patients treated at our hospital will pick,according to the severity of the patients with lesions,is divided into single lesion group (95 cases),the double branch lesion group (63 cases),three lesion group(49 cases),and the hospital at the same time will pick out of 52 cases of coronary heart disease patients as control group.For all patients serum FINS,LDL-C,TG,TC,hdl-c leel,Glu,TBil,GGT inspection.Results The patients with coronary heart disease group of FINS,LDL-C,TG,TC,Glu,GGT level is significantly higher than the control group patients,and patients with coronary heart disease group of HDL-C,TBil level significantly lower than the control group patients,P<0.05;And coronary heart disease (CHD)patients with the disease is severe,the higher the level of serum GGT,LDL-C accordingly,FINS will also greatly enhance the level,but will significantly reduce TBil level.Conclusion Serum GGT level and coronary heart disease (CHD) there is close relationship between occurrence,development,and can judge index as a clinical laboratory diagnosis of coronary artery disease.
, 百拇医药
Key words:Coronary heart disease;Serum - glutamine transferase;Clinical significance
在冠心病危险因素方面的报道多集中于血脂、血糖、血压、C-反应蛋白、胆红素、年龄等,但国外相关文献指出,血清γ-谷氨酰转移酶(GGT)水平的变化,可以对心血管疾病进行预示[1]。基于此,笔者进了如下实验探讨:
1 资料与方法
1.1一般资料 择取本院于2014年1月~2016年6月收治的冠心病患者207例,所有患者均经过冠脉造影检查,确保符合冠心病诊断标准,并择取同期收治的排除冠心病的患者52例作为对照组,所有患者均不存在急性脑血管意外、肝肾功能障碍、血液病、恶性肿瘤、酗酒等情况,均享有本次实验的知情权,符合医学伦理学意义要求。207例冠心病患者中,男121例,女86例,平均年龄为(70.6±10.5)岁;根据患者病变的严重程度,划分为单支病变组(95例)、双支病变组(63例)、三支病变组(49例)。对照组患者中,男30例,女22例,平均年龄为(67.6±8.9)岁。比较四组患者的一般资料,相应数据组间不存在满足统计学意义要求的差异,即P>0.05。, 百拇医药(黄荣宁 谭晓明 王正东 黎祖高 樊少勇 梁建华)