接种水痘减毒活疫苗对预防控制水痘的影响研究(1)
摘要:目的 探讨接种水痘减毒活疫苗对预防控制水痘的影响。方法 选取我中心登记 的需接受水痘减毒活疫苗接种的幼儿90例来进行统计分析,利用随机数表法将所有研究对象随机、均等的分为对照组和观察组各45例,对照组幼儿不接受水痘减毒活疫苗接种,观察组幼儿则接受,观察两组幼儿的水痘控制情况。结果 观察组45例幼儿均接受水痘减毒活疫苗接种,随访期间统计结果显示:不良反应发生率8.9%(4/45)。观察组水痘感染发生率4.4(2/45),对照组水痘感染发生率24.4%(11/45),观察组幼儿水痘感染发生率明显低于对照组(P<0.05)。结论 接种水痘减毒活疫苗对预防控制水痘效果突出,因此疾病预防控制中心要加强水痘减毒活疫苗接种力度,全面推进适龄儿童进行接种,实现水痘感染的有效控制。
关键词:接种;水痘减毒活疫苗;感染
Study on the Effect of Live Attenuated Vaccine Against Varicella on Prevention and Control of Chicken Pox
, 百拇医药
LIU Qiang
(Shifang Center for Disease Control and Prevention,Deyang 618400,Sichuan,China)
Abstract:Objective To investigate the effect of varicella vaccine inoculation on the prevention and control of varicella. Methods Our CDC were required to accept live varicella vaccination of young children in 90 cases for statistical analysis, using a random number table method all subjects were randomly and equally divided into control group and observation group of 45 cases the control group, children do not accept the varicella vaccine inoculation, the observation group of children received varicella, control observation of the two groups of children. Results In the observation group, 45 children received varicella vaccine inoculation, follow-up statistics showed that: the incidence of adverse reactions was 8.9% (4/45). The observation group of varicella infection rate was 4.4. (2/45), the control group 24.4% incidence of varicella infection (11/45), the observation group children varicella infection rate was significantly lower than the control group (P< 0.05). Conclusion Varicella attenuated live vaccine for the prevention and control of water outburst effect pox, The Disease prevention and control center to be extremely strong chicken pox vaccination efforts to promote school-age children to be vaccinated, to achieve effective control of chicken pox infection.
, 百拇医药
Key words:Vaccination; Live attenuated vaccine against Varicella; Infection
水痘是由水痘-帶状疱疹病毒引起的原发感染,以全身出疱疹为特征,属于急性传染病,可通过肢体、呼吸道进行传播,以发热及成批出现周身性红色斑丘疹、疱疹、痂疹为特征,多发于冬春两季,其传染力强,易感儿发病率可达95%以上,学龄前儿童多见,另外据资料显示,1/10的水痘患者容易引发肺炎、脑炎等并发症,严重威胁患者的身体健康,因此做好疫苗接种工作具有重要的社会意义[1-2]。本研究中以90例需接受水痘减毒活疫苗接种的幼儿为研究对象,采用对比分析法主要探讨接种水痘减毒活疫苗对预防控制水痘的影响,现将结果报道如下。
1 资料与方法
1.1一般资料 本次选取的90例研究对象均为我中心2012年4月~2013年6月登记的需接受水痘减毒活疫苗接种的幼儿,利用随机数表法将所有研究对象随机、均等的分为对照组和观察组各45例,现将患者资料整理如下:对照组男32例,女13例,年龄2~5岁,平均年龄(3.5±0.3)岁;体重:15~25kg,平均体重(20.9±1.7)kg。观察组男30例,女15例,年龄2~6岁,平均年龄(3.9±0.7)岁;体重:14~25 kg,平均体重(20.1±1.9)kg。纳入标准:幼儿家长均知情同意;经诊断均需要接受水痘减毒活疫苗接种。排除标准:先天性心脏病、严重肝肾疾病、严重心脑血管疾病、全身免疫系统疾病、神经系统障碍、配合度低等幼儿。两组幼儿在性别、年龄、体重等资料方面对比差异无统计学意义(P>0.05),具有可比性。, 百拇医药(刘强)
关键词:接种;水痘减毒活疫苗;感染
Study on the Effect of Live Attenuated Vaccine Against Varicella on Prevention and Control of Chicken Pox
, 百拇医药
LIU Qiang
(Shifang Center for Disease Control and Prevention,Deyang 618400,Sichuan,China)
Abstract:Objective To investigate the effect of varicella vaccine inoculation on the prevention and control of varicella. Methods Our CDC were required to accept live varicella vaccination of young children in 90 cases for statistical analysis, using a random number table method all subjects were randomly and equally divided into control group and observation group of 45 cases the control group, children do not accept the varicella vaccine inoculation, the observation group of children received varicella, control observation of the two groups of children. Results In the observation group, 45 children received varicella vaccine inoculation, follow-up statistics showed that: the incidence of adverse reactions was 8.9% (4/45). The observation group of varicella infection rate was 4.4. (2/45), the control group 24.4% incidence of varicella infection (11/45), the observation group children varicella infection rate was significantly lower than the control group (P< 0.05). Conclusion Varicella attenuated live vaccine for the prevention and control of water outburst effect pox, The Disease prevention and control center to be extremely strong chicken pox vaccination efforts to promote school-age children to be vaccinated, to achieve effective control of chicken pox infection.
, 百拇医药
Key words:Vaccination; Live attenuated vaccine against Varicella; Infection
水痘是由水痘-帶状疱疹病毒引起的原发感染,以全身出疱疹为特征,属于急性传染病,可通过肢体、呼吸道进行传播,以发热及成批出现周身性红色斑丘疹、疱疹、痂疹为特征,多发于冬春两季,其传染力强,易感儿发病率可达95%以上,学龄前儿童多见,另外据资料显示,1/10的水痘患者容易引发肺炎、脑炎等并发症,严重威胁患者的身体健康,因此做好疫苗接种工作具有重要的社会意义[1-2]。本研究中以90例需接受水痘减毒活疫苗接种的幼儿为研究对象,采用对比分析法主要探讨接种水痘减毒活疫苗对预防控制水痘的影响,现将结果报道如下。
1 资料与方法
1.1一般资料 本次选取的90例研究对象均为我中心2012年4月~2013年6月登记的需接受水痘减毒活疫苗接种的幼儿,利用随机数表法将所有研究对象随机、均等的分为对照组和观察组各45例,现将患者资料整理如下:对照组男32例,女13例,年龄2~5岁,平均年龄(3.5±0.3)岁;体重:15~25kg,平均体重(20.9±1.7)kg。观察组男30例,女15例,年龄2~6岁,平均年龄(3.9±0.7)岁;体重:14~25 kg,平均体重(20.1±1.9)kg。纳入标准:幼儿家长均知情同意;经诊断均需要接受水痘减毒活疫苗接种。排除标准:先天性心脏病、严重肝肾疾病、严重心脑血管疾病、全身免疫系统疾病、神经系统障碍、配合度低等幼儿。两组幼儿在性别、年龄、体重等资料方面对比差异无统计学意义(P>0.05),具有可比性。, 百拇医药(刘强)