翼状胬肉术后治疗用绷带镜的临床效果评价(1)
摘要：目的 评价翼状胬肉术后配戴治疗用绷带镜(博士伦纯视)的临床应用效果及安全性。 方法 选取60例(60眼)初发性翼状胬肉患者，随机分为两组，两组均行翼状胬肉切除联合自体角膜缘干细胞移植术，试验组30例30眼术后直接配戴治疗用绷带镜，对照组30例30眼术后不予配戴直接涂眼膏纱布包扎。术后观察7天出院，比较两组患者角膜上皮修复时间、眼部疼痛异物感症状评分。 结果 试验组和对照组的角膜上皮平均修复时间分别为(2.23±0.35)d和(2.63±0.69)d，两组患者比较差异有统计学意义(t=4.35，P<0.01)；试验组术后24 h、 48 h、 72 h、 96 h、 7 d的眼痛及异物感症状评分明显低于对照组， 差异具有统计学意义(P<0.05)。 结论 治疗用绷带镜能加速翼状胬肉术后角膜上皮修复时间，减轻眼部刺激症状，是一种安全、简便、有效提高患者术后眼部舒适度的方法。
关键词：翼状胬肉手术；治疗用绷带镜；角膜上皮；症状
Evaluation of Clinical Effect of Bandage with Postoperative Pterygium
, 百拇医药
SONG Yu-yan，XIE Ling，ZHOU Wei-ying
(Department of Ophthalmology，Occupational Diseases Hospital of Xinjiang Uygur Autonomous Region，Urumqi 830091，Xinjiang，China)
Abstract：Objective To evaluate the treatment of pterygium with bandage lenses(depending on the clinical application of Bausch&Lomb pure)effect and safety.Methods 60 cases(60 eyes)of primary pterygium were randomly divided into two groups，two groups underwent pterygium excision combined with autologous limbal stem cell transplantation，the experimental group 30 eyes of 30 patients after operation treatment wearing bandage lens，the control group wearing directly coated gauze ointment in 30 cases of 30 eyes were not observed after operation.After 7 days of discharge，compared two groups of patients with corneal epithelial healing time，eye pain，foreign body sensation symptom score.Results The average repair time of corneal epithelium in experimental group and control group respectively(2.23±0.35)d and(2.63±0.69)d，the two groups were statistically significant difference (t=4.35，P<0.01)；the experimental group after 24 h，48 h，72 h，96 h，7 d eye pain and foreign body sensation symptom score was significantly lower than the control group，the difference with statistical significance(P<0.05).Conclusion The treatment with a bandage mirror can repair time of corneal epithelium accelerated after pterygium surgery，relieve eye irritation，is a safe，simple and effective method to improve the postoperative ocular comfort.
, 百拇医药
Key words：Pterygium surgery；Treatment with bandage lens；Corneal epithelium；Symptoms
翼狀胬肉一般认为是受外界刺激而引起的局部球结膜纤维血管组织的一种慢性炎症性病变，可侵犯角膜。轻者眼部不适，影响美观，重者引起角膜散光或遮挡瞳孔而导致视力下降，还可引起睑球粘连影响眼球运动[1]。治疗以手术切除为主，目前多采用翼状胬肉切除联合自体结膜瓣移植或角膜缘干细胞移植术，术后复发率明显下降。无论选择哪一种手术方式，术后都避免不了因角膜溃疡及缝线刺激而引起的疼痛、畏光、流泪、异物感等不适。随着治疗性软性角膜接触镜在眼科的推广应用[2]，我们采用前瞻性随机对照研究，在接受翼状胬肉切除联合自体角膜缘干细胞移植术的患者中，应用治疗用绷带镜以促进角膜上皮愈合、减轻术后疼痛等角膜刺激症状，取得较好疗效。
1资料与方法
1.1一般资料 2015年1月～2016年4月在我院住院的单眼初发型翼状胬肉患者60例(60眼)，翼状胬肉均位于鼻侧，头部侵入角膜缘内2～5 mm，处于静止期，排除既往眼表手术史、外伤史、合并角膜病变及重症干眼症患者等，年龄40～70岁，病程1～15年。60例均行翼状胬肉切除联合自体角膜缘干细胞移植手术，术后患者随机分为两组，试验组30例(30眼)，男13例，女17例，平均年龄(56.23±7.82)岁，胬肉头部侵入角膜缘内平均(3.4±0.8)mm，术后直接配戴治疗用绷带镜； 对照组30例(30眼)，男14例，女16例，平均年龄(56.67±7.34)岁，胬肉头部侵入角膜缘内平均(3.3±1.0)mm，术后不配戴治疗用绷带镜。两组患者术后均给予抗生素滴眼液及促进角膜上皮修复的眼药水点眼治疗，未用止痛药。两组患者的性别、年龄及侵入角膜的范围比较无统计学差异(t=0.014，P>0.05)。, 百拇医药(宋玉艳 谢铃 周卫英)
关键词：翼状胬肉手术；治疗用绷带镜；角膜上皮；症状
Evaluation of Clinical Effect of Bandage with Postoperative Pterygium
, 百拇医药
SONG Yu-yan，XIE Ling，ZHOU Wei-ying
(Department of Ophthalmology，Occupational Diseases Hospital of Xinjiang Uygur Autonomous Region，Urumqi 830091，Xinjiang，China)
Abstract：Objective To evaluate the treatment of pterygium with bandage lenses(depending on the clinical application of Bausch&Lomb pure)effect and safety.Methods 60 cases(60 eyes)of primary pterygium were randomly divided into two groups，two groups underwent pterygium excision combined with autologous limbal stem cell transplantation，the experimental group 30 eyes of 30 patients after operation treatment wearing bandage lens，the control group wearing directly coated gauze ointment in 30 cases of 30 eyes were not observed after operation.After 7 days of discharge，compared two groups of patients with corneal epithelial healing time，eye pain，foreign body sensation symptom score.Results The average repair time of corneal epithelium in experimental group and control group respectively(2.23±0.35)d and(2.63±0.69)d，the two groups were statistically significant difference (t=4.35，P<0.01)；the experimental group after 24 h，48 h，72 h，96 h，7 d eye pain and foreign body sensation symptom score was significantly lower than the control group，the difference with statistical significance(P<0.05).Conclusion The treatment with a bandage mirror can repair time of corneal epithelium accelerated after pterygium surgery，relieve eye irritation，is a safe，simple and effective method to improve the postoperative ocular comfort.
, 百拇医药
Key words：Pterygium surgery；Treatment with bandage lens；Corneal epithelium；Symptoms
翼狀胬肉一般认为是受外界刺激而引起的局部球结膜纤维血管组织的一种慢性炎症性病变，可侵犯角膜。轻者眼部不适，影响美观，重者引起角膜散光或遮挡瞳孔而导致视力下降，还可引起睑球粘连影响眼球运动[1]。治疗以手术切除为主，目前多采用翼状胬肉切除联合自体结膜瓣移植或角膜缘干细胞移植术，术后复发率明显下降。无论选择哪一种手术方式，术后都避免不了因角膜溃疡及缝线刺激而引起的疼痛、畏光、流泪、异物感等不适。随着治疗性软性角膜接触镜在眼科的推广应用[2]，我们采用前瞻性随机对照研究，在接受翼状胬肉切除联合自体角膜缘干细胞移植术的患者中，应用治疗用绷带镜以促进角膜上皮愈合、减轻术后疼痛等角膜刺激症状，取得较好疗效。
1资料与方法
1.1一般资料 2015年1月～2016年4月在我院住院的单眼初发型翼状胬肉患者60例(60眼)，翼状胬肉均位于鼻侧，头部侵入角膜缘内2～5 mm，处于静止期，排除既往眼表手术史、外伤史、合并角膜病变及重症干眼症患者等，年龄40～70岁，病程1～15年。60例均行翼状胬肉切除联合自体角膜缘干细胞移植手术，术后患者随机分为两组，试验组30例(30眼)，男13例，女17例，平均年龄(56.23±7.82)岁，胬肉头部侵入角膜缘内平均(3.4±0.8)mm，术后直接配戴治疗用绷带镜； 对照组30例(30眼)，男14例，女16例，平均年龄(56.67±7.34)岁，胬肉头部侵入角膜缘内平均(3.3±1.0)mm，术后不配戴治疗用绷带镜。两组患者术后均给予抗生素滴眼液及促进角膜上皮修复的眼药水点眼治疗，未用止痛药。两组患者的性别、年龄及侵入角膜的范围比较无统计学差异(t=0.014，P>0.05)。, 百拇医药(宋玉艳 谢铃 周卫英)