地中海贫血和缺铁性贫血患者血常规检验的对比研究(1)
摘要：目的 对比研究地中海贫血和缺铁性贫血患者血常规检验结果。方法 选取地中海贫血和缺铁性贫血患者89例，依据其贫血类型分为地中海组45例和缺铁组44例，回顾性分析两组患者的贫血患者的血常规检验结果。结果 地中海组的红细胞体积分布宽度(RDW)、细胞平均体积(MCV)、紅细胞平均血红蛋白浓度(MCHC)水平均与缺铁组有显著差异(P<0.01)；而两组间的红细胞平均血红蛋白含量(MCH)水平无明显差异(P>0.05)。结论 血常规检验在地中海贫血及缺铁性贫血患者中，其RDW、MCV、MCHC值均具有明显差异，故而血常规检验在鉴别地中海贫血及缺铁性贫血中具有较好的诊断价值。
关键词：地中海贫血；缺铁性贫血；血常规
中图分类号：R556 文献标识码：A 文章编号：1006-1959(2017)17-0075-02 Comparative Study of Blood Routine Examination between Patients with Thalassemia and Iron Deficiency Anemia
, http://www.100md.com
FENG Mei，YUAN Xun
(1.Department of Clinical Laboratory，Guang'an Maternal and Child Health Care Hospital，Guang'an 638500，Sichuan，China；
2.Department of Clinical Laboratory，Guang'an Municipal Center for Disease Control and Prevention，Guang'an 638500，Sichuan，China)
Abstract：Objective To compare the results of blood test in patients with thalassemia and iron deficiency anemia.Methods 89 cases of thalassemia and iron deficiency anemia were selected.According to their anemia types，45 patients in the Mediterranean group and 44 cases in the iron deficiency group were analyzed retrospectively.The blood routine examination results of the two groups of anemia patients were analyzed retrospectively.Results The red cell volume distribution width(RDW)，mean cell volume(MCV)and the mean corpuscular hemoglobin concentration(MCHC)of the Mediterranean group were significantly different from those in the iron deficiency group(P<0.01)；While the two groups mean corpuscular hemoglobin(MCH)levels had no significant difference(P>0.05).Conclusion The blood test in patients with thalassemia and iron deficiency anemia，RDW，MCV，MCHC values were obviously different，so the blood test has better diagnostic value in the diagnosis of thalassemia and iron deficiency anemia.
, 百拇医药
Key words：Thalassemia；Iron deficiency anemia；Blood routine
贫血是指人体外周血红细胞容量减少，低于正常范围下限的一种常见的临床症状，严重影响患者的生长发育和身心健康。目前临床上最常见的贫血类型为地中海贫血和缺铁性贫血，这两种贫血均为小细胞低色素性贫血，其诊断和鉴别具有十分重要的意义。因不同贫血类型患者的红细胞体积分布宽度(RDW)、细胞平均体积(MCV)、红细胞平均血红蛋白浓度(MCHC)、红细胞平均血红蛋白含量(MCH)等血常规指标不同，故而可采用血常规进行鉴别地中海贫血和缺铁性贫血[1]。本次实验就地中海贫血和缺铁性贫血患者的血常规检验结果进行对比分析。
1 资料与方法
1.1一般资料
选取2015年2月～2016年1月我院收治的地中海贫血和缺铁性贫血患者89例，所有患者均有不同程度的乏力、食欲不振等症状，符合地中海贫血和缺铁性贫血的诊断标准：①地中海贫血：血红蛋白A2<2.5%或>3.5%，出现异常血红蛋白带；②缺铁性贫血：缺铁性贫血斑，血红蛋白<110 g/L，转铁蛋白饱和度<20%，红细胞压积<30%[2]。依据其贫血类型分为地中海组45例和缺铁组44例，两组患者的一般资料如下：地中海组男27例，女18例；年龄16～64岁，平均年龄(34.2±2.8)岁。缺铁组男25例、女19例；年龄18～63岁，平均年龄(35.6±3.2)岁。本次研究的所有患者均同意加入实验，并签署知情同意书。两组患者的性别及年龄比较，差异无统计学意义(P>0.05)，具有可比性。
1.2方法, 百拇医药(冯梅 袁珣)
关键词：地中海贫血；缺铁性贫血；血常规
中图分类号：R556 文献标识码：A 文章编号：1006-1959(2017)17-0075-02 Comparative Study of Blood Routine Examination between Patients with Thalassemia and Iron Deficiency Anemia
, http://www.100md.com
FENG Mei，YUAN Xun
(1.Department of Clinical Laboratory，Guang'an Maternal and Child Health Care Hospital，Guang'an 638500，Sichuan，China；
2.Department of Clinical Laboratory，Guang'an Municipal Center for Disease Control and Prevention，Guang'an 638500，Sichuan，China)
Abstract：Objective To compare the results of blood test in patients with thalassemia and iron deficiency anemia.Methods 89 cases of thalassemia and iron deficiency anemia were selected.According to their anemia types，45 patients in the Mediterranean group and 44 cases in the iron deficiency group were analyzed retrospectively.The blood routine examination results of the two groups of anemia patients were analyzed retrospectively.Results The red cell volume distribution width(RDW)，mean cell volume(MCV)and the mean corpuscular hemoglobin concentration(MCHC)of the Mediterranean group were significantly different from those in the iron deficiency group(P<0.01)；While the two groups mean corpuscular hemoglobin(MCH)levels had no significant difference(P>0.05).Conclusion The blood test in patients with thalassemia and iron deficiency anemia，RDW，MCV，MCHC values were obviously different，so the blood test has better diagnostic value in the diagnosis of thalassemia and iron deficiency anemia.
, 百拇医药
Key words：Thalassemia；Iron deficiency anemia；Blood routine
贫血是指人体外周血红细胞容量减少，低于正常范围下限的一种常见的临床症状，严重影响患者的生长发育和身心健康。目前临床上最常见的贫血类型为地中海贫血和缺铁性贫血，这两种贫血均为小细胞低色素性贫血，其诊断和鉴别具有十分重要的意义。因不同贫血类型患者的红细胞体积分布宽度(RDW)、细胞平均体积(MCV)、红细胞平均血红蛋白浓度(MCHC)、红细胞平均血红蛋白含量(MCH)等血常规指标不同，故而可采用血常规进行鉴别地中海贫血和缺铁性贫血[1]。本次实验就地中海贫血和缺铁性贫血患者的血常规检验结果进行对比分析。
1 资料与方法
1.1一般资料
选取2015年2月～2016年1月我院收治的地中海贫血和缺铁性贫血患者89例，所有患者均有不同程度的乏力、食欲不振等症状，符合地中海贫血和缺铁性贫血的诊断标准：①地中海贫血：血红蛋白A2<2.5%或>3.5%，出现异常血红蛋白带；②缺铁性贫血：缺铁性贫血斑，血红蛋白<110 g/L，转铁蛋白饱和度<20%，红细胞压积<30%[2]。依据其贫血类型分为地中海组45例和缺铁组44例，两组患者的一般资料如下：地中海组男27例，女18例；年龄16～64岁，平均年龄(34.2±2.8)岁。缺铁组男25例、女19例；年龄18～63岁，平均年龄(35.6±3.2)岁。本次研究的所有患者均同意加入实验，并签署知情同意书。两组患者的性别及年龄比较，差异无统计学意义(P>0.05)，具有可比性。
1.2方法, 百拇医药(冯梅 袁珣)
参见：首页 > 医疗版 > 疾病专题 > 血液内科 > 贫血 > 缺铁性贫血