重症肺炎患者血磷浓度的变化和意义(1)
摘要：目的 观察重症肺炎患者血磷的变化，探讨其临床意义。方法 89例重症肺炎患者，分为死亡组和存活组，分别于入院时、1 d后、4 d后、转出时(或死亡前)检测血磷浓度。结果 存活组与死亡组比较，入院时血磷浓度无明显差异(P>0.05)；在1 d后、4 d后，死亡组与存活组比较血磷浓度明显降低(P<0.05)；且随着时间的延长，死亡组患者的血磷浓度逐渐降低(P<0.05)；存活组在各时间点血磷浓度无明显差异(P>0.05)；死亡组死亡前与存活组转出时比较血磷浓度明显降低(P<0.01)。结论 重症肺炎患者随着病情的进展，血磷浓度逐渐降低，血磷浓度是反映重症肺炎患者预后的指标。
关键词：重症肺炎；血磷；预后
中图分类号：R472.3 文献标识码：A 文章编号：1006-1959(2017)19-0068-02
Changes and Significance of Serum Phosphorus Concentration in Patients with Severe Pneumonia
, http://www.100md.com
ZENG Jing
(Department of Critical Care Medicine，Zhuzhou Central Hospital，Zhuzhou 412000，Hunan，China)
Abstract：Objective To observe the changes of serum phosphorus in patients with severe pneumonia and explore its clinical significance.Methods 89 patients with severe pneumonia were divided into survival group and death group respectively.At the time of admission，1 d，4 d，roll out(or death) detection of serum phosphate concentration.Results Group comparison between survival group and death，the blood phosphorus concentration had no significant difference(P>0.05)；The serum phosphorus concentration was significantly decreased in the death group and the survival group after 1 d and 4 d(P<0.05).And with the extension of time，the blood phosphorus concentration of the patients in the death group decreased gradually(P<0.05)；There was no significant difference in blood phosphorus concentration at each time point(P>0.05)in the survival group.Compared with the survival group before death，the serum phosphorus concentration in the death group was significantly lower(P<0.01).Conclusion With the progression of the disease， the concentration of serum phosphorus in patients with severe pneumonia is gradually decreased，and the level of serum phosphorus is an indicator of the prognosis of patients with severe pneumonia.
, 百拇医药
Key words：Severe pneumonia；Serum phosphorus；Prognosis
重症肺炎是指起源于下呼吸道感染但并不局限于下呼吸道的危重甚至致死性的肺部感染性疾病[1-2]。重症肺炎是一个威胁人类健康的全球性问题，尤其是在发展中国家，不仅发病率高，死亡率也高。既往的研究已经证实了低蛋白血症及电解质紊乱等与肺炎的病情及近期预后密切相关[3]。本文分析5年来在我院ICU住院治疗的89例重症肺炎患者，观察患者入院后血磷的变化，探讨血磷在评价重症肺炎预后中的作用。
1资料与方法
1.1一般资料
依照重症肺炎的诊断标准，在我院住院患者中选取从2010年1月1日～2015年12月31日住入ICU治疗的89例重症肺炎患者，其中男性52例，女性37例，年龄在32～65岁，平均年龄(46.8±3.8)岁，既往无心、肺、肝、肾等慢性疾病史，患者入院时检测动脉血气分析氧分压均明显减低(PaO2≤55 mmHg)，血压均明显减低，入院血压均≤80/50 mmHg，根据患者最后是否死亡分为存活组(66例)和死亡组(23例)，死亡组男性14例，女性9例，存活组男性38例，女性28例。
1.2方法
所有患者从急诊科就诊后测量血压，行血气分析、血常规、肾功能和胸片检查，均符合重癥肺炎诊断标准，住入ICU。入ICU后均行气管插管、机械通气，予以积极扩容和升压治疗，入院后均予以积极抗感染和营养支持治疗。所有患者均于入院6 h内(此后简称入院时)抽取3.5 ml静脉血，采用雅培C8000仪器测量血磷浓度。此后所有患者均在入院1 d后、4 d后空腹分别抽取静脉血3.5 ml检测血磷浓度，并于转出ICU时(存活组)或死亡前(死亡组)抽取静脉血检测血磷浓度。, 百拇医药(曾璟)
关键词：重症肺炎；血磷；预后
中图分类号：R472.3 文献标识码：A 文章编号：1006-1959(2017)19-0068-02
Changes and Significance of Serum Phosphorus Concentration in Patients with Severe Pneumonia
, http://www.100md.com
ZENG Jing
(Department of Critical Care Medicine，Zhuzhou Central Hospital，Zhuzhou 412000，Hunan，China)
Abstract：Objective To observe the changes of serum phosphorus in patients with severe pneumonia and explore its clinical significance.Methods 89 patients with severe pneumonia were divided into survival group and death group respectively.At the time of admission，1 d，4 d，roll out(or death) detection of serum phosphate concentration.Results Group comparison between survival group and death，the blood phosphorus concentration had no significant difference(P>0.05)；The serum phosphorus concentration was significantly decreased in the death group and the survival group after 1 d and 4 d(P<0.05).And with the extension of time，the blood phosphorus concentration of the patients in the death group decreased gradually(P<0.05)；There was no significant difference in blood phosphorus concentration at each time point(P>0.05)in the survival group.Compared with the survival group before death，the serum phosphorus concentration in the death group was significantly lower(P<0.01).Conclusion With the progression of the disease， the concentration of serum phosphorus in patients with severe pneumonia is gradually decreased，and the level of serum phosphorus is an indicator of the prognosis of patients with severe pneumonia.
, 百拇医药
Key words：Severe pneumonia；Serum phosphorus；Prognosis
重症肺炎是指起源于下呼吸道感染但并不局限于下呼吸道的危重甚至致死性的肺部感染性疾病[1-2]。重症肺炎是一个威胁人类健康的全球性问题，尤其是在发展中国家，不仅发病率高，死亡率也高。既往的研究已经证实了低蛋白血症及电解质紊乱等与肺炎的病情及近期预后密切相关[3]。本文分析5年来在我院ICU住院治疗的89例重症肺炎患者，观察患者入院后血磷的变化，探讨血磷在评价重症肺炎预后中的作用。
1资料与方法
1.1一般资料
依照重症肺炎的诊断标准，在我院住院患者中选取从2010年1月1日～2015年12月31日住入ICU治疗的89例重症肺炎患者，其中男性52例，女性37例，年龄在32～65岁，平均年龄(46.8±3.8)岁，既往无心、肺、肝、肾等慢性疾病史，患者入院时检测动脉血气分析氧分压均明显减低(PaO2≤55 mmHg)，血压均明显减低，入院血压均≤80/50 mmHg，根据患者最后是否死亡分为存活组(66例)和死亡组(23例)，死亡组男性14例，女性9例，存活组男性38例，女性28例。
1.2方法
所有患者从急诊科就诊后测量血压，行血气分析、血常规、肾功能和胸片检查，均符合重癥肺炎诊断标准，住入ICU。入ICU后均行气管插管、机械通气，予以积极扩容和升压治疗，入院后均予以积极抗感染和营养支持治疗。所有患者均于入院6 h内(此后简称入院时)抽取3.5 ml静脉血，采用雅培C8000仪器测量血磷浓度。此后所有患者均在入院1 d后、4 d后空腹分别抽取静脉血3.5 ml检测血磷浓度，并于转出ICU时(存活组)或死亡前(死亡组)抽取静脉血检测血磷浓度。, 百拇医药(曾璟)
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